Consider the following statements regarding Thrombosis with Thrombocyt...
Thrombosis with Thrombocytopenia Syndrome (TTS):
Thrombosis with Thrombocytopenia Syndrome (TTS) is a rare but serious condition characterized by blood clots combined with low levels of platelets in the human body. Here are the detailed explanations of the statements given:
Statement 1:
- Correct: It is characterized by blood clots combined with low levels of platelets in the human body.
- Individuals with TTS experience abnormal clotting in their blood vessels, which can lead to severe complications such as strokes, heart attacks, and organ damage. Low platelet levels further increase the risk of bleeding.
Statement 2:
- Correct: It is more common among younger age groups.
- While TTS can affect individuals of any age, it has been observed to be more common among younger age groups. This may be due to factors such as genetic predisposition, lifestyle habits, and underlying health conditions that are more prevalent in younger populations.
In conclusion, both statements are correct regarding Thrombosis with Thrombocytopenia Syndrome (TTS). It is essential to raise awareness about this condition, especially among healthcare professionals and the general public, to ensure timely diagnosis and appropriate management.
Consider the following statements regarding Thrombosis with Thrombocyt...
Recently, AstraZeneca (AZ) has admitted its Covid vaccine may cause Thrombosis with Thrombocytopenia Syndrome (TTS).
- It is characterized by blood clots (thrombosis) combined with low levels of platelets (thrombocytopenia), which are necessary for blood clotting.
- It often involves unusual blood clot locations, such as in the brain (cerebral venous sinus thrombosis) or abdomen.
- Symptoms of TTS: Severe or persistent headaches, blurred vision, Shortness of breath, Chest pain, Leg swelling, Persistent abdominal pain and Easy bruising or tiny blood spots under the skin beyond the injection site etc.
- It is classified into two tiers based on the location of the blood clot and the severity of the symptoms.
- Tier 1:
- Uncommon site of thrombosis (like the brain-cerebral venous sinus thrombosis or the gut such as splanchnic vein, associated with bowel ischaemia and surgery, portal vein or other rare venous and arterial thromboses)
- Thrombosis in more common locations (deep vein thrombosis or pulmonary embolism)
- Platelet count is less than 1,50,000 per microlitre
- A positive anti-PF4 ELISA result is supportive, but not required for diagnosis.
- Tier 2:
- Common sites of thrombosis include leg or lungs (venous thromboembolism, deep vein thrombosis, pulmonary embolism)
- Platelet count is less than 1,50,000 per microlitre
- A positive anti-PF4 ELISA result is required.
- Tier 1 TTS carries a higher risk of mortality and morbidity than Tier 2. Tier 1 could be more common among younger age groups.
Hence both statements are correct.
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