Which of the following is not a Mendelian disorder?a)Haemophiliab)Turner’s syndromec)Cystic fibrosisd)Colour blindnessCorrect answer is option 'B'. Can you explain this answer?

Question

Which of the following is not a Mendelian disorder?a)Haemophiliab)Turner&#8217;s syndromec)Cystic fibrosisd)Colour blindnessCorrect answer is option 'B'. Can you explain this answer?

Answer

b turner's it is chromosomal disorder

Answer

Correct answer is B Turner's syndrome because it a chromosomal disorder not Mendelian disorder. if you like my answer please upvote me..... and follow me.....

Answer

Mosaic is not inherited. In an affected individual it occurs as a random event during cell division in early fetal development. As a result, some of an affected person's cells have only one copy of the x chromosome. But, one that is controlled by a single local in a inheritance pattern. In such case a mutation in a single gene can cause a disease that is inherited according to Mendel's law

Answer

Mendelian Disorders
Mendelian disorders, also known as single gene disorders, are genetic disorders that are caused by mutations in a single gene. These disorders follow the principles of Mendelian inheritance, which means they are inherited in a predictable pattern from one generation to the next. There are three types of Mendelian inheritance: autosomal dominant, autosomal recessive, and X-linked.

Distinguishing a Non-Mendelian Disorder
In order to determine which of the given options is not a Mendelian disorder, we need to understand the inheritance patterns of each disorder.

Hemophilia
- Hemophilia is a genetic disorder that affects the blood's ability to clot.
- It is caused by mutations in genes that provide instructions for making proteins involved in blood clotting.
- Hemophilia is an X-linked recessive disorder, meaning it is more commonly seen in males and can be passed on by carrier females.

Colour Blindness
- Colour blindness is a genetic disorder that affects a person's ability to perceive certain colors.
- It is caused by mutations in genes that provide instructions for making proteins involved in the perception of color.
- Colour blindness is an X-linked recessive disorder, similar to hemophilia, and is more commonly seen in males.

Thalassemia
- Thalassemia is a genetic disorder that affects the production of hemoglobin, the protein responsible for carrying oxygen in the blood.
- It is caused by mutations in genes that provide instructions for making the components of hemoglobin.
- Thalassemia can be inherited in an autosomal recessive manner, meaning it can affect both males and females.

Down Syndrome
- Downs syndrome, also known as trisomy 21, is a chromosomal disorder characterized by the presence of an extra copy of chromosome 21.
- It is not caused by a mutation in a single gene but rather by an error in the chromosomal distribution during cell division.
- Downs syndrome is not a Mendelian disorder because it does not follow the predictable patterns of inheritance seen in Mendelian disorders.

Conclusion
Out of the given options, Downs syndrome (option D) is not a Mendelian disorder. Unlike the other options, Downs syndrome is caused by an error in chromosomal distribution rather than a mutation in a single gene.

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