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R21/Matrix-M vaccine, recently seen in the news, is developed for the prevention of which one of the following diseases?
  • a)
    Mumps
  • b)
    Measles
  • c)
    Diphtheria
  • d)
    Malaria
Correct answer is option 'D'. Can you explain this answer?
Verified Answer
R21/Matrix-M vaccine, recently seen in the news, is developed for the ...
Vaccines manufacturer Serum Institute of India (SII) recently said it has started exports of 'R21/Matrix-M' malaria vaccine to Africa as part of the global fight against the disease.
About R21/Matrix-M Vaccine:
  • It is a new vaccine approved for the prevention of malaria in children.
  • It is the second malaria vaccinerecommended by the World Health Organization (WHO), following the RTS,S/AS01 vaccine, which received a WHO recommendation in 2021. 
  • The vaccine was developed by the Jenner Institute at Oxford University and the Serum Institute of India with support from the European and Developing Countries Clinical Trials Partnership ('EDCTP'), the Wellcome Trust, and the European Investment Bank ('EIB').
  • This low-cost, high-efficacy vaccine is already licensed by several African countries.
  • How does the R21/Matrix-M vaccine Works?
  • Vaccines work by putting the antigen, which is the piece of the virus or bacteria that our system recognises and responds to, in front of our immune cells. 
  • The R21/Matrix-M vaccine targets the plasmodium 'sporozoite', which is the first form of the malaria parasite entering the human body.
  • Only a few (10–100) sporozoites are injectedby infected mosquitoesbefore the parasite multiplies, making them the ideal targetfor a vaccine. 
  • R21 is a subunit vaccine that delivers parts of a proteinsecretedby the sporozoite that are bundled upwith a part of the hepatitis B virus that is known to trigger a strong immune response.
  • The vaccine also contains Matrix-M, an "adjuvant" which boosts the immune system’s response to make it more powerful and long-lasting.
Hence option d is the correct answer.
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R21/Matrix-M vaccine, recently seen in the news, is developed for the prevention of which one of the following diseases?a)Mumpsb)Measlesc)Diphtheriad)MalariaCorrect answer is option 'D'. Can you explain this answer?
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