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A.
Release of products of the reaction 
B.
Binding of substrate to the active site of the enzyme 
C.
Formation of enzyme-substrate complex 
D.
Alteration in the shape of the enzyme 
E.
Enzyme free to bind another molecule of substrate
Given above are the steps involved in the catalytic cycle of enzyme action. Choose the correct answer from the options given below: 
  • a)
    B > C > D > A > E 
  • b)
    B > D > C > A > E 
  • c)
    B > D > A > E > C 
  • d)
    B > E > D > C > A 
Correct answer is option 'B'. Can you explain this answer?
Verified Answer
A.Release of products of the reactionB.Binding of substrate to the act...
Ans: 2
Sol: During the state where substrate is bound to the enzyme active site, a new structure of the substrate called transition state structure is formed. Very soon, after the expected bond breaking/making is completed, the product is released from the active site
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Most Upvoted Answer
A.Release of products of the reactionB.Binding of substrate to the act...
Overview of Enzyme Action
Enzymes are biological catalysts that facilitate biochemical reactions by lowering the activation energy. Understanding their catalytic cycle is crucial in biochemistry.
Step-by-Step Breakdown of the Catalytic Cycle
- B: Binding of substrate to the active site of the enzyme
- The cycle begins with the substrate entering the active site of the enzyme, forming an enzyme-substrate complex.
- D: Alteration in the shape of the enzyme
- Upon binding, the enzyme undergoes a conformational change, enhancing the fit with the substrate and promoting the reaction.
- C: Formation of enzyme-substrate complex
- This alteration stabilizes the enzyme-substrate complex, which is essential for the reaction to proceed.
- A: Release of products of the reaction
- Once the reaction occurs, the enzyme catalyzes the conversion of substrates into products, which are then released from the active site.
- E: Enzyme free to bind another molecule of substrate
- After releasing the products, the enzyme returns to its original state, ready to catalyze another reaction cycle with a new substrate.
Conclusion
The correct order of the steps in the catalytic cycle of enzyme action is:
B > D > C > A > E
This sequence highlights the initial substrate binding, the necessary conformational changes, the formation of the enzyme-substrate complex, the release of products, and finally, the readiness of the enzyme for another substrate. Thus, option 'B' accurately represents the catalytic cycle of enzyme action.
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