Which of the statements given above is/are correct?i. Each myosin fila...
Overview of Myosin Filaments
Myosin is a crucial protein in muscle contraction and movement. Understanding its structure is essential for grasping how it functions.
Statement Analysis
- i. Each myosin filament is composed of many monomeric proteins known as Meromyosins.
- This statement is correct. Myosin filaments consist of two types of meromyosins: heavy meromyosin (HMM) and light meromyosin (LMM), which are dimeric proteins that form the filamentous structure.
- ii. The heavy meromyosin (HMM) consists of a tail and a globular head.
- This statement is also correct. HMM is the portion of the myosin molecule that includes the tail and the globular head, which is critical for interaction with actin filaments.
- iii. The cross arm of the myosin filament projects outwards at a regular distance and angle.
- This statement is correct as well. The myosin heads (cross bridges) indeed project outwards, allowing them to interact with actin filaments during contraction.
- iv. The globular head of myosin serves as an inactive enzyme with no binding sites for ATP.
- This statement is incorrect. The globular head of myosin is an active site that binds ATP, which is essential for muscle contraction and movement.
Conclusion
Based on the analysis, the correct statements are i, ii, and iii. Therefore, the correct answer is:
Option A: i and ii
Which of the statements given above is/are correct?i. Each myosin fila...
- Statement i is correct. Myosin filaments are indeed composed of multiple monomeric proteins called Meromyosins.
- Statement ii is incorrect. The heavy meromyosin (HMM) refers specifically to the globular head and short arm, while the light meromyosin (LMM) refers to the tail.
- Statement iii is correct. The cross arm of the myosin filament does project outwards at a regular distance and angle.
- Statement iv is incorrect. The globular head of myosin is an active ATPase enzyme with binding sites for ATP and active sites for actin.
Thus, the correct statements are i and iii, making the correct answer Option A.
Topic in NCERT: Structure of Contractile Proteins
Line in NCERT: "Each myosin (thick) filament is also a polymerised protein. Many monomeric proteins called Meromyosins constitute one thick filament. Each meromyosin has two important parts, a globular head with a short arm and a tail, the former being called the heavy meromyosin (HMM) and the latter, the light meromyosin (LMM). The HMM component, i.e.; the head and short arm projects outwards at regular distance and angle from each other from the surface of a polymerised myosin filament and is known as cross arm."