What role does the Distal Convoluted Tubule (DCT) play in the nephron?...
c) Reabsorption of HCO3-
The Distal Convoluted Tubule (DCT) plays a crucial role in:
- Reabsorption of ions like HCO3- (bicarbonate), sodium, and calcium.
- Regulation of pH by secreting hydrogen ions (H⁺) and reabsorbing bicarbonate (HCO3⁻).
- Water reabsorption under the influence of hormones like antidiuretic hormone (ADH) and aldosterone. However, the reabsorption of water is not the primary function in the DCT (compared to the collecting duct and loop of Henle).
What role does the Distal Convoluted Tubule (DCT) play in the nephron?...
Role of the Distal Convoluted Tubule (DCT) in the Nephron
The Distal Convoluted Tubule (DCT) is a crucial segment of the nephron, playing a significant role in the reabsorption and secretion processes that regulate electrolyte balance, acid-base homeostasis, and overall fluid balance in the body.
Key Functions of the DCT:
- Selective Reabsorption:
- The DCT is primarily responsible for the reabsorption of important ions such as sodium (Na+) and chloride (Cl-).
- It also reabsorbs bicarbonate (HCO3-), which is essential for maintaining acid-base balance.
- Reabsorption of HCO3-:
- The correct answer, option 'C', highlights the DCT's role in the reabsorption of bicarbonate.
- This process is vital as bicarbonate acts as a buffer, neutralizing acids in the blood and helping to maintain a stable pH level.
- Active Secretion:
- The DCT is involved in the active secretion of various substances, including potassium (K+) and hydrogen ions (H+).
- This helps regulate potassium levels and plays a role in acid-base balance.
- Fluid and Electrolyte Balance:
- The reabsorption and secretion processes in the DCT are influenced by hormones such as aldosterone, which promotes sodium reabsorption and potassium secretion.
Conclusion:
In summary, the Distal Convoluted Tubule is primarily responsible for the reabsorption of bicarbonate (HCO3-), along with sodium and chloride, while also playing a role in electrolyte and acid-base balance. This function is critical for maintaining homeostasis in the body.