Complete failure of the anterior lobe of pituitary causesa) Addison's disease b) Acromegaly c) Cushing's disease d) Simmond's disease Correct answer is option 'D'. Can you explain this answer?

Question

Complete failure of the anterior lobe of pituitary causesa)                                  Addison's disease                               b)                                  Acromegaly                               c)                                  Cushing's disease                               d)                                  Simmond's disease                               Correct answer is option 'D'. Can you explain this answer?

Answer

This is because addison and cushing are due to degeneration of adrenal gland and acromegaly is due to oversecretion of growth hormone in adults simmond disease is due to atrophy of anterior lobe of pituitary gland.

Answer

The correct answer is D..simmonds disease is caused by destruction of anterior lobe of pituitary gland from any cause. The most common cause is post-partum necrosis of anterior lobe of pituitary gland. The appearance of many patients suffering from the disease bears a striking resemblance with myxodema. An incomplete syndrome usually results in hypogonadism as the predominanting feature. The therapy of Simmonds disease is at present unsatisfactory, but the production of pituitary trophic factors in relatively pure form offers hope for future.....

Answer

Right tanay

Answer

Complete failure of the anterior lobe of pituitary causes Simmonds disease.

Simmonds disease, also known as pituitary cachexia or pituitary apoplexy, is a rare condition characterized by the complete failure of the anterior lobe of the pituitary gland. This gland is located at the base of the brain and is responsible for producing and releasing various hormones that regulate important bodily functions.

The anterior lobe of the pituitary gland is responsible for producing and releasing several hormones, including growth hormone (GH), adrenocorticotropic hormone (ACTH), thyroid-stimulating hormone (TSH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), and prolactin. These hormones play crucial roles in regulating growth, metabolism, reproduction, and other bodily functions.

Effects of complete failure of the anterior lobe of pituitary (Simmonds disease):

1. Growth hormone deficiency: The lack of growth hormone can lead to stunted growth in children and a decrease in muscle mass and bone density in adults. It can also cause fatigue, weakness, and increased fat accumulation.

2. Adrenocorticotropic hormone deficiency: The absence of ACTH results in adrenal insufficiency, leading to low levels of cortisol. This can cause symptoms such as fatigue, weight loss, low blood pressure, and electrolyte imbalances.

3. Thyroid-stimulating hormone deficiency: Without TSH, the thyroid gland is not stimulated to produce thyroid hormones, leading to hypothyroidism. Symptoms may include fatigue, weight gain, cold intolerance, and constipation.

4. Luteinizing hormone and follicle-stimulating hormone deficiency: In women, the lack of LH and FSH can cause menstrual irregularities, infertility, and decreased libido. In men, it can lead to decreased testosterone levels, erectile dysfunction, and infertility.

5. Prolactin deficiency: Prolactin is responsible for milk production in breastfeeding women. Its deficiency can result in the inability to produce breast milk.

Overall, the complete failure of the anterior lobe of the pituitary gland in Simmonds disease leads to a variety of hormonal deficiencies, affecting multiple systems in the body. Prompt diagnosis and appropriate hormone replacement therapy are essential to manage the symptoms and improve the quality of life for individuals with this condition.

Top Courses for NEETView all

Biology Class 11

Daily Test for NEET Preparation

Topic-wise MCQ Tests for NEET

NEET Mock Test Series - Updated 2026 Pattern

Physics Class 11

Top Courses for NEET

Top Courses for NEET

Related Content

About NEET

NEET Preparation Material

How to Prepare for NEET Exam?

NCERT Based Study Material

NEET Mock Tests

Other Popular Exams

Company