Introduction:
Lizards are known for their ability to regenerate their tails, which is a unique feature among reptiles. The regenerative process involves various cells and mechanisms, and understanding them can provide insights into regenerative medicine.

Regeneration of tail in lizards:
The regeneration of the tail in lizards involves various cells, including:

1. Blastemal cells:
Blastemal cells are undifferentiated cells that are responsible for the regeneration of the tail. These cells are located at the base of the tail and are activated upon tail autotomy (self-amputation).

2. Epithelial cells:
Epithelial cells are responsible for the formation of the wound epidermis, which covers the amputation site and is critical for tail regeneration. These cells differentiate into different cell types depending on the spatial and temporal cues during regeneration.

3. Schwann cells:
Schwann cells are responsible for the formation of the nerve sheath and play a crucial role in guiding axon regeneration.

4. Fibroblasts:
Fibroblasts are responsible for the formation of the extracellular matrix, which provides structural support for the regenerating tissue.

5. Immune cells:
Immune cells are involved in the clearance of debris and the prevention of infection during the regenerative process.

Conclusion:
In conclusion, the regeneration of the tail in lizards involves various cells and mechanisms, including blastemal cells, epithelial cells, Schwann cells, fibroblasts, and immune cells. Understanding these cells and their interactions can provide insights into regenerative medicine and the development of new therapies for tissue repair and regeneration.