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In reaction~P.E. graph , highest potential energy state in the absence of enzyme or higher potential energy state in the presence of enzyme which represent the transition state?
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In reaction~P.E. graph , highest potential energy state in the absence...
Any chemical reaction includes formation of transition state between reactant and product. Formation of transition state requires high energy content of reactant molecules for alignment of reacting groups, formation of transient unstable charges, rearrangements of chemical bonds etc. The energy required for formation of transition state is termed as activation energy. Enzymes enhance the rate of reaction by lowering down the activation energy of transition state.  In given graph, energy of substrate is higher than that of product reflecting the endothermic nature of reaction. And B is the activation energy in absence of enzyme which is lowered down to A in presence of enzyme.
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In reaction~P.E. graph , highest potential energy state in the absence of enzyme or higher potential energy state in the presence of enzyme which represent the transition state?
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