Which hormone of anterior pituatory is inhibited by dopaminea)Growth h...
The hormone of anterior pituitary that is inhibited by dopamine is prolactin. This is known as the prolactin inhibitory hormone (PIH).
Role of dopamine in prolactin regulation:
- Dopamine is released from the hypothalamus and travels to the anterior pituitary via the hypophyseal portal system.
- In the anterior pituitary, dopamine binds to receptors on lactotroph cells that secrete prolactin.
- Dopamine inhibits the release of prolactin from lactotroph cells.
- When dopamine levels decrease, such as during pregnancy or breastfeeding, prolactin levels increase.
Effects of prolactin:
- Stimulates milk production in mammary glands (lactation)
- Inhibits ovulation and menstruation in females (temporary infertility)
- May affect sexual behavior and other physiological processes
Why is dopamine important for prolactin regulation?
- Imbalances in dopamine levels can lead to hyperprolactinemia, a condition where prolactin levels are too high.
- Hyperprolactinemia can cause symptoms such as infertility, irregular periods, decreased libido, and breast milk production in non-pregnant individuals.
- Dopamine agonists (drugs that mimic dopamine) are used to treat hyperprolactinemia.
In summary, dopamine inhibits the release of prolactin from lactotroph cells in the anterior pituitary. This is important for regulating lactation, fertility, and other physiological processes.
Which hormone of anterior pituatory is inhibited by dopaminea)Growth h...
Dopamine regulate the secretion of hormone from an
terior pituitary dopamine supports growth hormone and inhibit prolactin it also blocks gonadotropin hormone and TSH.