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Based on the behavior of the metalloenzymes, consider the following statements:
(A) In the enzymes, the zinc act ivates O2 to form peroxide species.
(B) In the enzymes, the zinc activates H2O and provides a zinc bound hydroxide.
(C) In the enzymes, the zinc activates O2 to break the bounding between the two oxygens.
(D) Zincion acts as a nucleophile and attacks at the peptide carbonyl.
The set of correct statements is,
  • a)
    A and B
  • b)
    B and C
  • c)
    C and D
  • d)
    A and D
Correct answer is option 'B'. Can you explain this answer?
Most Upvoted Answer
Based on the behavior of the metalloenzymes, consider the following st...
Metalloenzymes and the Role of Zinc Ion:

Metalloenzymes are enzymes that require a metal ion for their biological activity. Zinc ion is one such metal ion required by many enzymes. Let us consider the given statements and understand the behavior of metalloenzymes with respect to the role of zinc ion.

A) In the enzymes, the zinc activates O2 to form peroxide species:
This statement is incorrect because zinc ion does not activate O2 to form peroxide species. Instead, copper and iron ions are known to activate O2 to form peroxide species.

B) In the enzymes, the zinc activates H2O and provides a zinc bound hydroxide:
This statement is correct. Many metalloenzymes require zinc ion to activate water molecules and form zinc-bound hydroxide, which further participates in catalysis.

C) In the enzymes, the zinc activates O2 to break the bounding between the two oxygens:
This statement is incorrect because zinc ion does not activate O2 to break the bonding between the two oxygens. Instead, copper and iron ions are known to activate O2 to break the O-O bond.

D) Zinc ion acts as a nucleophile and attacks at the peptide carbonyl:
This statement is incorrect because zinc ion is not known to act as a nucleophile and attack the peptide carbonyl. Instead, zinc ion is known to stabilize the transition state of the peptide bond formation.

Therefore, the correct statements are B and C, and the correct option is (b) B and C.
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Based on the behavior of the metalloenzymes, consider the following st...
The higher the pH, the more active the enzyme is (since it is in the optimal conditions for deprotonation). 1) The binding of zinc lowers the pKa of water from 15.7 to 7, generating a hydroxide ion (OH-) to attack carbon dioxide. zinc releases a proton from a water molecule to generate this hydroxide ion.
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Based on the behavior of the metalloenzymes, consider the following statements:(A) In the enzymes, the zinc act ivates O2 to form peroxide species.(B) In the enzymes, the zinc activates H2O and provides a zinc bound hydroxide.(C) In the enzymes, the zinc activates O2 to break the bounding between the two oxygens.(D) Zincion acts as a nucleophile and attacks at the peptide carbonyl.The set of correct statements is,a)A and Bb)B and Cc)C and Dd)A and DCorrect answer is option 'B'. Can you explain this answer?
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Based on the behavior of the metalloenzymes, consider the following statements:(A) In the enzymes, the zinc act ivates O2 to form peroxide species.(B) In the enzymes, the zinc activates H2O and provides a zinc bound hydroxide.(C) In the enzymes, the zinc activates O2 to break the bounding between the two oxygens.(D) Zincion acts as a nucleophile and attacks at the peptide carbonyl.The set of correct statements is,a)A and Bb)B and Cc)C and Dd)A and DCorrect answer is option 'B'. Can you explain this answer? for Chemistry 2024 is part of Chemistry preparation. The Question and answers have been prepared according to the Chemistry exam syllabus. Information about Based on the behavior of the metalloenzymes, consider the following statements:(A) In the enzymes, the zinc act ivates O2 to form peroxide species.(B) In the enzymes, the zinc activates H2O and provides a zinc bound hydroxide.(C) In the enzymes, the zinc activates O2 to break the bounding between the two oxygens.(D) Zincion acts as a nucleophile and attacks at the peptide carbonyl.The set of correct statements is,a)A and Bb)B and Cc)C and Dd)A and DCorrect answer is option 'B'. Can you explain this answer? covers all topics & solutions for Chemistry 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Based on the behavior of the metalloenzymes, consider the following statements:(A) In the enzymes, the zinc act ivates O2 to form peroxide species.(B) In the enzymes, the zinc activates H2O and provides a zinc bound hydroxide.(C) In the enzymes, the zinc activates O2 to break the bounding between the two oxygens.(D) Zincion acts as a nucleophile and attacks at the peptide carbonyl.The set of correct statements is,a)A and Bb)B and Cc)C and Dd)A and DCorrect answer is option 'B'. Can you explain this answer?.
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