Kupffer cells are found in ?

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Liver

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Liver...!!!

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Liver .

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¶¶ Liver¶¶

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Liver.

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Kupffer cell is also known as stellate macrophages.. And the located in liver linings the wall of the sinusoids. ☺☺

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Kupffer cells  are macrophages found in the sinusoids of the liver.

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Kupffer cells (also known as stellate sinusoidal macrophages or Kupffer-Browicz cells) are macrophages found in the sinusoids of the liver. In fact, Kupffer cells make up 80% to 90% of all the macrophages in the entire human body.

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Liver..,

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Liver!!

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In LIVER. ,

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**LIVER**

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Macrophages  found in Sinusoids of the liver.

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Liver...

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In Liver...

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IN LIVER.!!

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Liver....!!

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Kupffer cells are found in liver

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In liver.

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Liver..

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Liver.'

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In my liver.

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*It's liver.

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Liver is the ans for ur ques...

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Ans is liver

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Liver!

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Liver..  .

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Yeah answer is liver

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--Liver--

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Kupffer cells are specialized macrophages found in the liver. They play a crucial role in maintaining the health and function of the liver by carrying out various important functions. Here, we will discuss in detail about the location and functions of Kupffer cells.

Location of Kupffer Cells:
Kupffer cells are primarily located within the liver sinusoids, which are the specialized blood vessels that carry blood from the hepatic artery and portal vein to the central vein of the liver lobule. These cells are strategically positioned along the sinusoids, allowing them to efficiently interact with the blood passing through the liver.

Functions of Kupffer Cells:
1. Phagocytosis:
Kupffer cells are highly efficient phagocytes that can engulf and remove cellular debris, toxins, pathogens, and other foreign substances from the bloodstream. They play a vital role in the immune defense of the liver by clearing harmful substances and preventing their entry into the systemic circulation.

2. Detoxification:
The liver is responsible for detoxifying various substances, and Kupffer cells contribute to this process. They are involved in the breakdown and elimination of toxic substances, including drugs, alcohol, and metabolic waste products.

3. Antigen Presentation:
Kupffer cells can process antigens from pathogens and present them to other immune cells, such as T cells and B cells. This helps in initiating an immune response against the invading pathogens.

4. Cytokine Production:
Kupffer cells produce and release various cytokines, which are small proteins involved in cell signaling. These cytokines regulate immune responses, inflammation, and tissue repair in the liver.

5. Iron Recycling:
The liver plays a crucial role in iron metabolism, and Kupffer cells contribute to this process by recycling iron from aged or damaged red blood cells. They break down the hemoglobin and release iron for reuse in the production of new red blood cells.

6. Fibrosis Regulation:
In case of liver injury or inflammation, Kupffer cells can release factors that promote fibrosis or scarring. This can be beneficial in limiting tissue damage and promoting wound healing, but excessive fibrosis can lead to liver dysfunction.

In conclusion, Kupffer cells are specialized macrophages located in the liver sinusoids. They perform various essential functions, including phagocytosis, detoxification, antigen presentation, cytokine production, iron recycling, and regulation of fibrosis. These functions contribute to the overall health and proper functioning of the liver.

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