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Metal ions required for functioning of enzyme is
  • a)
    Holoenzyme
  • b)
    Co-enzyme
  • c)
    Prosthetic group
  • d)
    Co-factor
Correct answer is option 'D'. Can you explain this answer?
Verified Answer
Metal ions required for functioning of enzyme isa)Holoenzymeb)Co-enzym...
A number of enzymes require metal ions for their activity which form coordination bonds with side chains at the active site and at the same time form one or more cordination bonds with the substrate, e.g., zinc is a cofactor for the proteolytic enzyme carboxypeptidase.
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Most Upvoted Answer
Metal ions required for functioning of enzyme isa)Holoenzymeb)Co-enzym...
Co-factor: Metal ions required for functioning of enzyme
Metal ions play a crucial role in the functioning of enzymes by serving as essential co-factors. These metal ions are required for the enzyme to catalyze specific reactions efficiently.
  • Holoenzyme: The complete, catalytically active form of an enzyme is known as a holoenzyme. It consists of both the protein component (apoenzyme) and the necessary co-factor, such as a metal ion.
  • Co-enzyme: While co-enzymes are organic molecules that assist enzymes in their function, metal ions specifically serve as inorganic co-factors. They help in stabilizing the enzyme's structure and facilitating the catalytic reaction.
  • Prosthetic group: Metal ions can also be tightly bound to the enzyme as a prosthetic group, essential for its activity. These ions are not easily dissociated from the enzyme during its catalytic cycle.


In the context of metal ions as co-factors, they are necessary for the proper functioning of many enzymes. Without these metal ions, the enzyme may not be able to perform its catalytic function effectively. Therefore, metal ions are crucial for the activity of certain enzymes and are classified as co-factors in enzyme catalysis.
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Metal ions required for functioning of enzyme isa)Holoenzymeb)Co-enzymec)Prosthetic groupd)Co-factorCorrect answer is option 'D'. Can you explain this answer?
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