Which of the following muscular disorders is inherited?a)Tetanyb)Muscu...
Progressive degeneration of skeletal muscle mostly due to genetic disorder is muscular dystrophy where as tetany is muscular spasm due to low calcium in body fluid. Myasthenia gravis is an anto immume disorder leading to paralysis of skeletal muscles. Botulism is rare and dangerous type of food poisoning caused by bacterium Clostridium Botulinum.
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Which of the following muscular disorders is inherited?a)Tetanyb)Muscu...
Muscular dystrophy is an inherited X linked recessive disorder It's caused due to the mutation in DMA gene(Duchenne muscular dystrophy).
Which of the following muscular disorders is inherited?a)Tetanyb)Muscu...
Inherited Muscular Disorder: Muscular Dystrophy
Muscular dystrophy is a group of genetic disorders that lead to muscle weakness and degeneration. It is primarily characterized by progressive muscle wasting and loss of function. Here’s a detailed explanation of why muscular dystrophy is inherited:
Genetic Basis
- Muscular dystrophies are caused by mutations in genes responsible for muscle structure and function.
- The most common type, Duchenne Muscular Dystrophy (DMD), is linked to mutations in the dystrophin gene located on the X chromosome.
- Since this gene is located on the X chromosome, males are predominantly affected, as they have only one X chromosome.
Types of Inheritance
- Different types of muscular dystrophy exhibit various inheritance patterns:
- Duchenne and Becker Muscular Dystrophy: X-linked recessive.
- Myotonic Dystrophy: Autosomal dominant.
- Limb-girdle Muscular Dystrophy: Can be autosomal dominant or recessive.
Other Disorders Explained
- Tetany: A condition marked by muscle cramps and spasms, usually caused by electrolyte imbalances, not inherited.
- Myasthenia Gravis: An autoimmune disorder characterized by weakness in the skeletal muscles; it is not inherited.
- Botulism: Caused by a toxin from the bacterium Clostridium botulinum; it is an infectious condition, not genetic.
Conclusion
In summary, muscular dystrophy is the only muscular disorder listed that is inherited due to its genetic basis, making option 'B' the correct choice. Understanding these distinctions is crucial for recognizing the nature of these conditions, especially in the context of genetics and inheritance patterns.
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