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Keeping in view the fluid mosaic model for the structure of cell membrane which one of the following statements is correct with respect to the movement of lipids and proteins from one liquid monolayer to the other described as flip flop movement- (1)while proteins can flip-flop ,lipids can not (2)neither Lipid , nor protein can flip flop (3) both Lipid and protein can flip flop (4)lipids can rarely flip-flop, proteins cannot Ans is (4), can u please explain?
Verified Answer
Keeping in view the fluid mosaic model for the structure of cell membr...
The Movement of lipid molecules from one lipid monolayer to another monolayer is called flip-flop movement. Flip-flop movement is rarely found in lipid molecules whereas it remain absent in protein molecules. singer and Nicolson (1972) suggested the widely accepted fluid mosaic model of biological membranes.
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Most Upvoted Answer
Keeping in view the fluid mosaic model for the structure of cell membr...
Lipid can flip flop, but most large proteins do not flip-flop due to their extensive polar regions, which are unfavorable in the hydrophobic core of a membrane bilayer.
so answer 4 is right
Community Answer
Keeping in view the fluid mosaic model for the structure of cell membr...
Introduction:
The fluid mosaic model is a widely accepted model that describes the structure of the cell membrane. According to this model, the cell membrane is composed of a fluid phospholipid bilayer with various proteins embedded within it. One aspect of cell membrane dynamics is the movement of lipids and proteins between the two layers of the bilayer, known as flip-flop movement.

Explanation:
The correct statement regarding the flip-flop movement of lipids and proteins in the cell membrane is option (4): lipids can rarely flip-flop, proteins cannot. Let's discuss the reasons behind this statement.

Lipid Flip-Flop:
1. Different lipid composition: The two layers of the phospholipid bilayer have different lipid compositions. The outer layer typically contains more phosphatidylcholine, while the inner layer contains more phosphatidylserine and phosphatidylethanolamine. This difference in lipid composition creates a barrier for lipids to spontaneously flip-flop between the layers.
2. Flip-flop rate: The spontaneous flip-flop of lipids is energetically unfavorable due to the hydrophobic tails of the phospholipids. It requires overcoming a significant energy barrier, making the flip-flop movement relatively rare. However, certain enzymes called flippases can facilitate the movement of specific lipids from one layer to another.

Protein Flip-Flop:
1. Structural constraints: Proteins are larger and more complex molecules compared to lipids. Their structures are often tightly integrated into the lipid bilayer, with specific regions interacting with the hydrophobic core. This integration restricts the ability of proteins to flip-flop between the layers.
2. Function and stability: Proteins play essential roles in various cellular processes and maintain specific orientations and conformations within the membrane. Flip-flop movement of proteins could disrupt their functional interactions and stability, making it unfavorable for proteins to undergo flip-flop.

Summary:
In summary, according to the fluid mosaic model, lipids can rarely flip-flop between the layers of the cell membrane due to differences in lipid composition and the energetically unfavorable process. On the other hand, proteins are structurally constrained and have functional and stability considerations, which prevent them from undergoing flip-flop movement. Therefore, option (4) - lipids can rarely flip-flop, proteins cannot - is the correct statement.
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Keeping in view the fluid mosaic model for the structure of cell membrane which one of the following statements is correct with respect to the movement of lipids and proteins from one liquid monolayer to the other described as flip flop movement- (1)while proteins can flip-flop ,lipids can not (2)neither Lipid , nor protein can flip flop (3) both Lipid and protein can flip flop (4)lipids can rarely flip-flop, proteins cannot Ans is (4), can u please explain?
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Keeping in view the fluid mosaic model for the structure of cell membrane which one of the following statements is correct with respect to the movement of lipids and proteins from one liquid monolayer to the other described as flip flop movement- (1)while proteins can flip-flop ,lipids can not (2)neither Lipid , nor protein can flip flop (3) both Lipid and protein can flip flop (4)lipids can rarely flip-flop, proteins cannot Ans is (4), can u please explain? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about Keeping in view the fluid mosaic model for the structure of cell membrane which one of the following statements is correct with respect to the movement of lipids and proteins from one liquid monolayer to the other described as flip flop movement- (1)while proteins can flip-flop ,lipids can not (2)neither Lipid , nor protein can flip flop (3) both Lipid and protein can flip flop (4)lipids can rarely flip-flop, proteins cannot Ans is (4), can u please explain? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Keeping in view the fluid mosaic model for the structure of cell membrane which one of the following statements is correct with respect to the movement of lipids and proteins from one liquid monolayer to the other described as flip flop movement- (1)while proteins can flip-flop ,lipids can not (2)neither Lipid , nor protein can flip flop (3) both Lipid and protein can flip flop (4)lipids can rarely flip-flop, proteins cannot Ans is (4), can u please explain?.
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