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Examination of blood of a person suspected of having anemia, shows large, immature, nucleated erythrocytes without haemoglobin. Supple-menting his diet with which of the following, is likely to alleviate his symptoms? [2006]
  • a)
    Folic acid and cobalamine
  • b)
    Riboflavin
  • c)
    Iron compounds
  • d)
    Thiamine
Correct answer is option 'A'. Can you explain this answer?
Verified Answer
Examination of blood of a person suspected of having anemia, shows lar...
Folic Acid (Cyanocobalamine vit. B12) works in the formation and maturation of RBCs. In the deficiency of this RBCs formation decreases and the formed RBCs will not mature i.e. they will not loose the nucleus and hence remain nucleated and lack haemoglobin. Such RBCs cannot carry oxygen & person suffers from anaemia. Supplementing his diet with folic acid and cobalamine will lead to the increased formation and proper maturation of enucleated RBCs with haemoglobin and eliminate anaemia.
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Most Upvoted Answer
Examination of blood of a person suspected of having anemia, shows lar...
Examination of Blood in Anemia:
- Anemia is a condition characterized by a decrease in the number of red blood cells (RBCs) or a decrease in the amount of hemoglobin within the RBCs.
- The examination of blood in a person suspected of having anemia reveals large, immature, nucleated erythrocytes without hemoglobin.

Understanding the Symptoms:
- Large, immature, nucleated erythrocytes without hemoglobin indicate a disruption in the normal process of red blood cell maturation and hemoglobin synthesis.
- The presence of nucleated red blood cells suggests that the bone marrow is releasing immature cells into the bloodstream in an attempt to compensate for the deficiency.

Identifying the Deficiency:
- To alleviate the symptoms of anemia, it is important to identify the underlying deficiency responsible for the abnormal erythrocyte development.
- The most common causes of anemia include deficiencies in iron, vitamin B12 (cobalamine), and folic acid.
- Riboflavin (vitamin B2) and thiamine (vitamin B1) deficiencies are not typically associated with anemia.

Supplementing the Diet:
- The correct answer is option A: Folic acid and cobalamine.
- Folic acid and cobalamine are essential for the normal maturation of red blood cells and the synthesis of hemoglobin.
- Folic acid is required for DNA synthesis, which is crucial for the production of new cells, including red blood cells.
- Cobalamine is necessary for the proper functioning of enzymes involved in red blood cell maturation and the synthesis of DNA.
- Supplementing the diet with folic acid and cobalamine can help alleviate the symptoms of anemia by promoting the production of mature red blood cells with sufficient hemoglobin.

Conclusion:
- In this case, the examination of blood reveals large, immature, nucleated erythrocytes without hemoglobin, indicative of anemia.
- Supplementing the diet with folic acid and cobalamine is likely to alleviate the symptoms by supporting the normal maturation of red blood cells and the synthesis of hemoglobin.
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Community Answer
Examination of blood of a person suspected of having anemia, shows lar...
Deficiency of vitamin B12(cobalamine) and folate can result in megaloblastic anaemia. This type of anaemina may be accompanied with ineffective erythropoiesis. Neurological abnormalities are peculiar symptom of the disease. The vitamins are intertwined biochemically so that the final common pathway that impairs DNA synthesis in hematopoietic cells.
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Examination of blood of a person suspected of having anemia, shows large, immature, nucleated erythrocytes without haemoglobin. Supple-menting his diet with which of the following, is likely to alleviate his symptoms? [2006]a)Folic acid and cobalamineb)Riboflavinc)Iron compoundsd)ThiamineCorrect answer is option 'A'. Can you explain this answer?
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Examination of blood of a person suspected of having anemia, shows large, immature, nucleated erythrocytes without haemoglobin. Supple-menting his diet with which of the following, is likely to alleviate his symptoms? [2006]a)Folic acid and cobalamineb)Riboflavinc)Iron compoundsd)ThiamineCorrect answer is option 'A'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about Examination of blood of a person suspected of having anemia, shows large, immature, nucleated erythrocytes without haemoglobin. Supple-menting his diet with which of the following, is likely to alleviate his symptoms? [2006]a)Folic acid and cobalamineb)Riboflavinc)Iron compoundsd)ThiamineCorrect answer is option 'A'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Examination of blood of a person suspected of having anemia, shows large, immature, nucleated erythrocytes without haemoglobin. Supple-menting his diet with which of the following, is likely to alleviate his symptoms? [2006]a)Folic acid and cobalamineb)Riboflavinc)Iron compoundsd)ThiamineCorrect answer is option 'A'. Can you explain this answer?.
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