ABO blood groups in humans are controlled by the gene I. It has three ...
The three calle/es in ABO blood groups in humans can produce six different genotypes and four different phenotypes
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ABO blood groups in humans are controlled by the gene I. It has three ...
: IA, IB, and i. The IA allele codes for the A antigen on red blood cells, the IB allele codes for the B antigen, and the i allele does not code for either antigen.
The IA and IB alleles are codominant, meaning that if an individual has both alleles, they will express both A and B antigens on their red blood cells. Therefore, there are four possible phenotypes for the ABO blood group: A (IAIA or IAi), B (IBIB or IBi), AB (IAIB), and O (ii).
The IA and IB alleles are dominant over the i allele, so individuals with the ii genotype will have the O blood group. However, individuals with the IAi or IBi genotypes will still express the A or B antigens, respectively, on their red blood cells.
The inheritance of ABO blood groups follows simple Mendelian genetics. Each individual has two copies of the I gene, one from each parent. The possible genotypes and corresponding phenotypes are as follows:
- IAIA: genotype for blood group A, phenotype A
- IAIB: genotype for blood group AB, phenotype AB
- IAi: genotype for blood group A, phenotype A
- IBIB: genotype for blood group B, phenotype B
- IBi: genotype for blood group B, phenotype B
- ii: genotype for blood group O, phenotype O
It is important to note that the ABO blood group system is just one of many blood group systems in humans, and there are other factors that can influence blood compatibility and transfusion reactions.
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