Which of the following hormones will stimulate gluconeogenesis?a)miner...
Glucocorticoids stimulate gluconeogenesis. Similarly, glucagon also stimulates the process of gluconeogenesis which also contributes to hyperglycemia.
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Which of the following hormones will stimulate gluconeogenesis?a)miner...
Option[d] as--->
Gluconeogenesis is stimulated by the diabetogenic hormones (glucagon, growth hormone, epinephrine, and cortisol).
Which of the following hormones will stimulate gluconeogenesis?a)miner...
Glucose is an essential fuel source for the body, and it is crucial to maintain stable blood glucose levels. Gluconeogenesis is the process by which new glucose is synthesized from non-carbohydrate sources, such as amino acids and glycerol. Hormones play a significant role in regulating gluconeogenesis, and among the options provided, glucocorticoids and glucagon are the hormones that stimulate this process.
1. Glucocorticoids:
- Glucocorticoids, such as cortisol, are steroid hormones released by the adrenal cortex in response to stress.
- They promote gluconeogenesis by increasing the breakdown of proteins and fats, releasing amino acids and glycerol, which can be converted into glucose.
- Glucocorticoids also inhibit the uptake and utilization of glucose by peripheral tissues, directing it to the liver for gluconeogenesis.
- This hormone is essential for maintaining blood glucose levels during fasting or prolonged stress.
2. Glucagon:
- Glucagon is a peptide hormone released by the alpha cells of the pancreas in response to low blood glucose levels.
- It acts by stimulating gluconeogenesis in the liver and inhibiting glycogen synthesis.
- Glucagon promotes the breakdown of stored glycogen into glucose, which is then released into the bloodstream.
- It also enhances the breakdown of fats, providing additional substrates for gluconeogenesis.
- Together, these actions increase the production and release of glucose, helping to raise blood glucose levels.
Hence, the correct answer is option D: glucocorticoids and glucagon. Both hormones work synergistically to stimulate gluconeogenesis and maintain blood glucose levels during periods of fasting or stress.
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