Useful biological products obtained from transgenic animals to treat diseases

Transgenic animals are animals that have been genetically modified by inserting foreign genes into their DNA. These animals can be used to produce useful biological products that can be used to treat various diseases. The following are some of the diseases that can be treated using biological products from transgenic animals:

i. Emphysema: Emphysema is a chronic lung disease that is caused by the destruction of the alveoli in the lungs. Transgenic mice have been developed that produce higher levels of an enzyme called alpha-1-antitrypsin (AAT). AAT is a protein that helps protect the lungs from damage caused by enzymes that break down lung tissue. AAT produced by transgenic mice can be used to treat emphysema.

ii. AIDS: Acquired immunodeficiency syndrome (AIDS) is caused by the human immunodeficiency virus (HIV). Transgenic goats have been developed that produce a human antibody called 2G12. This antibody can neutralize a wide range of HIV strains and can be used to treat AIDS.

iii. Cystic fibrosis: Cystic fibrosis is a genetic disorder that affects the lungs, pancreas, and other organs. Transgenic pigs have been developed that produce a human protein called CFTR. CFTR helps regulate the flow of salt and water in the lungs and other organs. CFTR produced by transgenic pigs can be used to treat cystic fibrosis.

iv. Phenylketonuria: Phenylketonuria (PKU) is a genetic disorder that affects the way the body processes an amino acid called phenylalanine. Transgenic mice have been developed that produce a human enzyme called phenylalanine hydroxylase. This enzyme helps break down phenylalanine in the body. Phenylalanine hydroxylase produced by transgenic mice can be used to treat PKU.

Therefore, the correct option is B) Only i, iii, and iv as biological products from transgenic animals can be used to treat Emphysema, Cystic fibrosis, and Phenylketonuria.

Because option 1,3,4 are autosomal means gene related. By transgenic animal gene related diseases can be fixed. Where AIDS is a std.