Radioactive thymidine when added to the medium surrounding living mamm...
Heterochromatin is a specialized chromosome material which remains tightly coiled and stains darkly in interphase. Euchromatin is that portion of the chromosome that stains with low intensity and uncoils during interphase. In the beginning of S-sphase, DNA replication occurs. DNA replication can occur in diffuse/ less tightly coiled euchromatin.
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Radioactive thymidine when added to the medium surrounding living mamm...
Explanation:
When radioactive thymidine is added to the medium surrounding living mammalian cells, it gets incorporated into the newly synthesized DNA. The incorporation of radioactive thymidine occurs during the S-phase of the cell cycle when DNA replication takes place.
Euchromatin:
Euchromatin is a loosely packed form of chromatin that is actively transcribed and is involved in gene expression. It contains genes that are actively being transcribed or are poised for transcription. During the S-phase, when DNA replication occurs, euchromatin is actively involved in DNA synthesis. Therefore, if cells are exposed to radioactive thymidine as soon as they enter the S-phase, the radioactive thymidine will be incorporated into the newly synthesized DNA in euchromatin. Hence, the euchromatin is expected to become radioactive.
Heterochromatin:
Heterochromatin is a tightly packed form of chromatin that is transcriptionally inactive. It contains genes that are not actively being transcribed. During the S-phase, heterochromatin is generally not involved in DNA replication. Therefore, if cells are exposed to radioactive thymidine as soon as they enter the S-phase, the heterochromatin is not expected to become radioactive as it is not actively replicating DNA.
Nucleolus:
The nucleolus is a specialized subcompartment of the nucleus involved in ribosome biogenesis. It contains the genes for ribosomal RNA (rRNA) synthesis. During the S-phase, the nucleolus is not directly involved in DNA replication. Therefore, if cells are exposed to radioactive thymidine as soon as they enter the S-phase, the nucleolus is not expected to become radioactive.
Conclusion:
In conclusion, when cells are exposed to radioactive thymidine as soon as they enter the S-phase, the radioactive thymidine is expected to be incorporated into the newly synthesized DNA in euchromatin. Therefore, the correct answer is option B - Euchromatin.
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