Kinetochore is a button like structure embedded in the surface of a centromeric chromatin of most eukaryotic mitotic chromosome...

Kinetochore
Kinetochore is a crucial structure located at the surface of the centromere of a chromosome. It plays a vital role in cell division, specifically in the process of mitosis and meiosis.

Function
- Kinetochore serves as the attachment point for spindle fibers during cell division.
- It helps in the movement of chromosomes to opposite poles of the cell during anaphase.
- It also regulates the timing of chromosome separation and ensures equal distribution of genetic material to daughter cells.

Structure
- Kinetochore is a complex protein structure that forms on the centromere region of chromosomes.
- It consists of multiple protein complexes that interact with microtubules of the spindle fibers.
- The outer kinetochore interacts with the microtubules, while the inner kinetochore binds to the centromere region of the chromosome.

Importance
- Proper functioning of kinetochores is essential for accurate segregation of chromosomes during cell division.
- Defects in kinetochore structure or function can lead to aneuploidy, a condition characterized by an abnormal number of chromosomes in daughter cells.
In conclusion, kinetochore is a granule located at the surface of the centromere of a chromosome, and it plays a crucial role in ensuring accurate chromosome segregation during cell division.