GATE Exam  >  GATE Questions  >  The reactions leading to the formation of ami... Start Learning for Free
The reactions leading to the formation of amino acids from the TCA cycle intermediates are  
  • a)
    carboxylation
  • b)
    isomerization
  • c)
    transamination
  • d)
    decarboxylation
Correct answer is option 'C'. Can you explain this answer?
Verified Answer
The reactions leading to the formation of amino acids from the TCA cyc...
View all questions of this test
Most Upvoted Answer
The reactions leading to the formation of amino acids from the TCA cyc...
Reactions leading to the formation of amino acids from the TCA cycle intermediates:

The correct option is 'C', transamination.

Explanation:

The TCA (tricarboxylic acid) cycle, also known as the citric acid cycle or Krebs cycle, is a series of chemical reactions that occur in the mitochondria of cells. It is an essential metabolic pathway that generates energy in the form of ATP and provides intermediates for various biosynthetic pathways, including the formation of amino acids.

Transamination:
Transamination is a key reaction in amino acid metabolism, where an amino group (-NH2) is transferred from an amino acid to a keto acid, resulting in the formation of a new amino acid and a new keto acid. In the context of the TCA cycle, transamination reactions play a crucial role in the synthesis of amino acids from TCA cycle intermediates.

Role of transamination in amino acid synthesis:
1. α-Ketoglutarate (an intermediate of the TCA cycle) can be transaminated to form glutamate. This reaction is catalyzed by the enzyme glutamate dehydrogenase.
2. Glutamate can further undergo transamination to form other amino acids. For example:
- Transamination of glutamate with oxaloacetate forms aspartate, catalyzed by the enzyme aspartate aminotransferase.
- Transamination of glutamate with pyruvate forms alanine, catalyzed by the enzyme alanine aminotransferase.
- Transamination of glutamate with 3-phosphoglycerate forms serine, catalyzed by the enzyme phosphoserine aminotransferase.

These transamination reactions allow the conversion of TCA cycle intermediates into amino acids, which are essential building blocks for proteins and play vital roles in various biological processes. The newly formed amino acids can then be utilized for protein synthesis or other metabolic pathways.

In summary, transamination reactions play a crucial role in the formation of amino acids from TCA cycle intermediates. They facilitate the transfer of amino groups from TCA cycle intermediates to keto acids, resulting in the synthesis of different amino acids.
Explore Courses for GATE exam

Similar GATE Doubts

The reactions leading to the formation of amino acids from the TCA cycle intermediates are a)carboxylationb)isomerizationc)transaminationd)decarboxylationCorrect answer is option 'C'. Can you explain this answer?
Question Description
The reactions leading to the formation of amino acids from the TCA cycle intermediates are a)carboxylationb)isomerizationc)transaminationd)decarboxylationCorrect answer is option 'C'. Can you explain this answer? for GATE 2024 is part of GATE preparation. The Question and answers have been prepared according to the GATE exam syllabus. Information about The reactions leading to the formation of amino acids from the TCA cycle intermediates are a)carboxylationb)isomerizationc)transaminationd)decarboxylationCorrect answer is option 'C'. Can you explain this answer? covers all topics & solutions for GATE 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for The reactions leading to the formation of amino acids from the TCA cycle intermediates are a)carboxylationb)isomerizationc)transaminationd)decarboxylationCorrect answer is option 'C'. Can you explain this answer?.
Solutions for The reactions leading to the formation of amino acids from the TCA cycle intermediates are a)carboxylationb)isomerizationc)transaminationd)decarboxylationCorrect answer is option 'C'. Can you explain this answer? in English & in Hindi are available as part of our courses for GATE. Download more important topics, notes, lectures and mock test series for GATE Exam by signing up for free.
Here you can find the meaning of The reactions leading to the formation of amino acids from the TCA cycle intermediates are a)carboxylationb)isomerizationc)transaminationd)decarboxylationCorrect answer is option 'C'. Can you explain this answer? defined & explained in the simplest way possible. Besides giving the explanation of The reactions leading to the formation of amino acids from the TCA cycle intermediates are a)carboxylationb)isomerizationc)transaminationd)decarboxylationCorrect answer is option 'C'. Can you explain this answer?, a detailed solution for The reactions leading to the formation of amino acids from the TCA cycle intermediates are a)carboxylationb)isomerizationc)transaminationd)decarboxylationCorrect answer is option 'C'. Can you explain this answer? has been provided alongside types of The reactions leading to the formation of amino acids from the TCA cycle intermediates are a)carboxylationb)isomerizationc)transaminationd)decarboxylationCorrect answer is option 'C'. Can you explain this answer? theory, EduRev gives you an ample number of questions to practice The reactions leading to the formation of amino acids from the TCA cycle intermediates are a)carboxylationb)isomerizationc)transaminationd)decarboxylationCorrect answer is option 'C'. Can you explain this answer? tests, examples and also practice GATE tests.
Explore Courses for GATE exam
Signup for Free!
Signup to see your scores go up within 7 days! Learn & Practice with 1000+ FREE Notes, Videos & Tests.
10M+ students study on EduRev