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Which of the following feature(s) should be present in a protein to generate strong immune response (antibody production) in an animal?
I. At least one B-cell epitope
II. At least one T-cell epitope
III. Proteolytic cleavage site(s)
  • a)
    I only
  • b)
    II and III
  • c)
    I and III
  • d)
    I, II and III
Correct answer is option 'D'. Can you explain this answer?
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Which of the following feature(s) should be present in a protein to ge...
Key Features for Strong Immune Response in Proteins:

B-cell Epitope:
- B-cell epitopes are regions on a protein that can be recognized by antibodies.
- Presence of at least one B-cell epitope is important for generating an antibody response in animals.
- Antibodies produced against B-cell epitopes help in targeting specific proteins for immune response.

T-cell Epitope:
- T-cell epitopes are regions on a protein that can be recognized by T-cells.
- Presence of at least one T-cell epitope is crucial for initiating cellular immunity.
- T-cell epitopes help in activating T-cells to further stimulate antibody production and immune response.

Proteolytic Cleavage Site(s):
- Proteolytic cleavage sites are locations on a protein where enzymes can cleave and break down the protein.
- Presence of proteolytic cleavage sites can help in processing the protein into smaller peptides that can be presented to immune cells for recognition.
- Cleavage sites play a role in antigen presentation and triggering an immune response.

Conclusion:
- In order to generate a strong immune response and antibody production in animals, a protein should ideally possess all three features: at least one B-cell epitope, at least one T-cell epitope, and proteolytic cleavage sites. These features work together to stimulate both humoral and cellular immune responses, leading to a robust immune reaction against the protein.
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Which of the following feature(s) should be present in a protein to generate strong immune response (antibody production) in an animal?I. At least one B-cell epitopeII. At least one T-cell epitopeIII. Proteolytic cleavage site(s)a)I onlyb)II and IIIc)I and IIId)I, II and IIICorrect answer is option 'D'. Can you explain this answer?
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Which of the following feature(s) should be present in a protein to generate strong immune response (antibody production) in an animal?I. At least one B-cell epitopeII. At least one T-cell epitopeIII. Proteolytic cleavage site(s)a)I onlyb)II and IIIc)I and IIId)I, II and IIICorrect answer is option 'D'. Can you explain this answer? for IIT JAM 2024 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about Which of the following feature(s) should be present in a protein to generate strong immune response (antibody production) in an animal?I. At least one B-cell epitopeII. At least one T-cell epitopeIII. Proteolytic cleavage site(s)a)I onlyb)II and IIIc)I and IIId)I, II and IIICorrect answer is option 'D'. Can you explain this answer? covers all topics & solutions for IIT JAM 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Which of the following feature(s) should be present in a protein to generate strong immune response (antibody production) in an animal?I. At least one B-cell epitopeII. At least one T-cell epitopeIII. Proteolytic cleavage site(s)a)I onlyb)II and IIIc)I and IIId)I, II and IIICorrect answer is option 'D'. Can you explain this answer?.
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