Hargobind Khorana is known for his experiments based on which of the f...
Hargobind Khorana: Discoverer of DNA Ligase Enzyme
Introduction:
Hargobind Khorana was an Indian-American biochemist who received the Nobel Prize in Physiology or Medicine in 1968 for his contribution to the deciphering of the genetic code.
Discovery of DNA Ligase Enzyme:
Khorana's research on nucleic acids led him to discover the DNA ligase enzyme. In 1967, he and his team were able to synthesize the first wholly artificial gene, using the enzyme DNA ligase to link together 77 nucleotides in the correct sequence.
Significance of Discovery:
The discovery of the DNA ligase enzyme was a significant contribution to the field of genetics. The enzyme plays a crucial role in the replication and repair of DNA by joining together the ends of DNA strands, allowing for the formation of a continuous strand. This discovery has led to advancements in genetic engineering, gene therapy, and the development of new drugs.
Conclusion:
Khorana's discovery of the DNA ligase enzyme was a significant contribution to the field of genetics and has led to advancements in various areas of science. His research and discoveries have paved the way for further exploration in the field of genetics and have had a profound impact on the world of science and medicine.
Hargobind Khorana is known for his experiments based on which of the f...
Hargobind Singh is known for his discovery of synthetic gene with DNA ligase enzyme
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