Oxidation of pyruvate to CO2and H2O occurs througha)citric acid cycleb)Tricarboxylic cyclec)Krebs cycled)All the aboveCorrect answer is option 'C'. Can you explain this answer?

Question

Answer

It has to op D coz Krebs cycle itself is known as citric acid cycle and tricarboxylic cycle.

Answer

Correct answer should be 'D'...But here the answer is (C),which is wrong because Citric acid cycle and tricarboxylic cycle are other names of Krebs cycle

Answer

I think correct answer is option D.  Pyruvate formed glycolysis is oxidised Co2 and H2O in krebs cycle or citric cycle or tricarboxylic acid cycle. krebs cycle involves in the oxidation of acetyl CoA into Co2 and H2O. So, the correct option is (d) .

Answer

It occurs in mitochondrial matrix once refer in respiration lesson

Answer

Overview:
The oxidation of pyruvate to CO2 and H2O is a crucial step in cellular respiration. It occurs through a series of reactions known as the citric acid cycle, also referred to as the tricarboxylic acid cycle or Krebs cycle. This cycle takes place in the mitochondria of eukaryotic cells and is responsible for generating ATP and reducing power molecules such as NADH and FADH2. The cycle consists of several key steps, each catalyzed by specific enzymes.

Citric Acid Cycle:
1. Acetyl-CoA Formation: Before entering the citric acid cycle, pyruvate is converted to acetyl-CoA. This step occurs in the mitochondrial matrix and involves the removal of one carbon from pyruvate, resulting in the release of CO2 and the formation of acetyl-CoA.

2. Citrate Formation: Acetyl-CoA combines with oxaloacetate, a four-carbon compound, to form citrate. This reaction is catalyzed by the enzyme citrate synthase.

3. Isomerization and Decarboxylation Reactions: The citrate molecule undergoes a series of isomerization reactions, leading to the generation of isocitrate. Isocitrate is then oxidized to α-ketoglutarate, releasing CO2 and reducing NAD+ to NADH in the process. This reaction is catalyzed by the enzyme isocitrate dehydrogenase.

4. α-Ketoglutarate Oxidation: α-ketoglutarate is further oxidized to succinyl-CoA, producing one molecule of NADH and releasing another molecule of CO2. This step is catalyzed by the enzyme α-ketoglutarate dehydrogenase.

5. Succinyl-CoA Conversion: Succinyl-CoA is converted to succinate, with the production of one molecule of GTP (which can be converted to ATP) and the reduction of FAD to FADH2. This reaction is catalyzed by the enzyme succinyl-CoA synthetase.

6. Succinate Oxidation: Succinate is oxidized to fumarate, reducing FAD to FADH2. This reaction is catalyzed by the enzyme succinate dehydrogenase.

7. Fumarate Conversion: Fumarate is then hydrated to form malate, catalyzed by the enzyme fumarase.

8. Malate Oxidation: Malate is oxidized to oxaloacetate, producing one molecule of NADH. This reaction is catalyzed by the enzyme malate dehydrogenase, completing the citric acid cycle.

Conclusion:
The oxidation of pyruvate to CO2 and H2O occurs through the citric acid cycle, which is also referred to as the tricarboxylic acid cycle or Krebs cycle. This cycle involves a series of enzymatic reactions that result in the generation of ATP and reducing power molecules such as NADH and FADH2. Each step of the cycle is catalyzed by specific enzymes, leading to the complete oxidation of pyruvate and the production of CO2 and H2O. Therefore, the correct answer is option 'D' - all of the above (citric acid cycle

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