Enzyme Renin is secreted by :-[MP PMT 2001]a)Cells of stomachb)Cells of intestinec)The cortical cells of kidneyd)The cells of juxtaglomerular apparatus of kidneyCorrect answer is option 'D'. Can you explain this answer?

Question

Answer

The enzyme 'Renin' is secreted by the cells of juxtaglomerular apparatus (JG apparatus)..in response to decrease in GFR..option D

Answer

Cells of stomach secret rennin. whereas renin is secreted by JG  cells of kidney to  increase GFR ..so d is crt

Answer

Answer is option d) The cells of juxtaglomerular apparatus of kidney

Answer

Juxtaglomerular cells produce Renin. These cells are similar to epithelium & are located in the tunica media of the afferent arterioles as they enter the glomeruli. The Juxtaglomerular cells secretes renin in response to
• Stimulation of the beta-1-adrenergic receptor.
• Decrease in renal perfusion pressure.
• Decrease in NaCl concentration at the macula dense, often due to decrease in glomerular filtration.

Answer

JGA cell secret renin when there is a fall in BP

Answer

Enzyme Renin is secreted by the cells of juxtaglomerular apparatus of the kidney.

Explanation:
Renin is an enzyme that plays a crucial role in the regulation of blood pressure and fluid balance in the body. It is primarily synthesized and secreted by the cells of the juxtaglomerular apparatus (JGA) in the kidney. Let's understand the details of this process.

1. Juxtaglomerular Apparatus (JGA):
The JGA is a specialized structure located in the kidney, specifically at the point where the distal convoluted tubule (DCT) comes into contact with the afferent arteriole. It consists of three main components: the macula densa, granular (juxtaglomerular) cells, and extraglomerular mesangial cells.

2. Renin Production:
The granular (juxtaglomerular) cells within the JGA are responsible for the production and secretion of renin. These cells are modified smooth muscle cells located in the walls of the afferent arteriole. They contain specialized granules that store and release renin.

3. Stimuli for Renin Secretion:
Renin secretion is regulated by several factors including:
- Decreased blood pressure: When blood pressure drops, it signals the granular cells to release renin.
- Sympathetic nervous system activation: Activation of the sympathetic nervous system, such as during stress or low blood volume, stimulates renin release.
- Decreased sodium concentration: A decrease in sodium levels in the distal convoluted tubule, detected by the macula densa cells, triggers renin secretion.

4. Renin Function:
Once released into the bloodstream, renin acts as an enzyme that converts angiotensinogen (a protein produced by the liver) into angiotensin I. This is the first step in the renin-angiotensin-aldosterone system, a complex hormonal cascade that regulates blood pressure and fluid balance.

5. Renin-Angiotensin-Aldosterone System:
Angiotensin I, produced by renin, is further converted into angiotensin II by the action of angiotensin-converting enzyme (ACE). Angiotensin II is a potent vasoconstrictor, causing blood vessels to constrict and leading to an increase in blood pressure. It also stimulates the release of aldosterone, a hormone that promotes sodium reabsorption and potassium excretion in the kidneys, further contributing to blood pressure regulation.

In conclusion, the enzyme renin is produced and secreted by the cells of the juxtaglomerular apparatus (JGA) in the kidney. Its secretion is regulated by various factors and plays a crucial role in maintaining blood pressure and fluid balance in the body.

Similar NEET Doubts

Which one of the following statements is true regarding digestion and absorption of food in humans? [2009]

Juxtaglomerular apparatus is made up of

Which of the following supports the idea that the secretion of enzymes from the pancreas is controlled by hormones?

Secretin hormone is secreted by?

Which one of the following statements is true regarding digestion and absorption of food in humans?

Top Courses for NEETView all

Biology Class 11

Daily Test for NEET Preparation

NEET Mock Test Series 2025

Topic-wise MCQ Tests for NEET

Physics Class 11

Top Courses for NEET

Top Courses for NEET

Suggested Free Tests

Related Content

About NEET

NEET Preparation Material

How to Prepare for NEET Exam?

NCERT Based Study Material

NEET Mock Tests

Other Popular Exams

Company