Q: Which of the following gastic cells indirectly help in erythropoies...
Erythropoiesis is a process of production of red blood cells. The parietal cells of the stomach are gastric cells that indirectly help in erythropiesis. These cells produce glycoprotein known as a gastric intrinsic factors (GIF). This factors plays important role in in the absorption of vitamin B12 in the ileum of small intestine. The vitamin B12, in turn, is essential in the process of erythropoiesis for differentiation of erythroblasts.
So, correct answer is "Parietal cells"...
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Q: Which of the following gastic cells indirectly help in erythropoies...
Answer:
The correct answer is d) Parietal cells.
Explanation:
Erythropoiesis is the process of producing red blood cells (RBCs) in the bone marrow. It is a complex process that requires multiple factors and cells to work together. While gastric cells are primarily involved in the production of gastric juices and the digestion of food, certain cells indirectly contribute to erythropoiesis.
Here, we will discuss the role of parietal cells in erythropoiesis.
Parietal Cells:
Parietal cells, also known as oxyntic cells, are found in the gastric glands of the stomach lining. They secrete hydrochloric acid (HCl) and intrinsic factor. HCl aids in the digestion of proteins, while intrinsic factor is essential for the absorption of vitamin B12 in the small intestine.
Role in Erythropoiesis:
Erythropoiesis requires an adequate supply of vitamin B12, which is necessary for the maturation of RBCs. Intrinsic factor secreted by parietal cells binds to vitamin B12 in the stomach and protects it from degradation in the acidic environment. This complex is then transported to the small intestine, where it is absorbed and utilized in the production of RBCs.
Without intrinsic factor, the body cannot absorb sufficient amounts of vitamin B12, leading to a condition called pernicious anemia. Pernicious anemia is characterized by a decreased production of RBCs, resulting in symptoms such as fatigue, weakness, and shortness of breath.
In conclusion, parietal cells indirectly contribute to erythropoiesis by secreting intrinsic factor, which enables the absorption of vitamin B12. Adequate levels of vitamin B12 are crucial for the maturation of RBCs and the prevention of pernicious anemia.
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