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Types of mutations?
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Types of mutations?
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Types of mutations?
Types of Mutations:
Mutation refers to changes in the DNA sequence that can lead to variations in traits. There are various types of mutations, each with different effects on an organism.

1. Point Mutations:
- Point mutations involve changes in a single nucleotide base in the DNA sequence.
- They can be classified into three types:
- Silent mutations: These mutations do not result in any change in the amino acid sequence due to redundancy in the genetic code.
- Missense mutations: These mutations lead to the substitution of one amino acid with another, potentially altering protein function.
- Nonsense mutations: These mutations result in the formation of a premature stop codon, leading to the production of a truncated protein.

2. Insertions and Deletions:
- Insertions involve the addition of nucleotide bases in the DNA sequence, while deletions involve the removal of nucleotide bases.
- These mutations can lead to frameshift mutations, where the reading frame of the genetic code is altered, resulting in a non-functional protein.

3. Chromosomal Mutations:
- Chromosomal mutations involve changes in the structure or number of chromosomes.
- Examples of chromosomal mutations include:
- Duplication: A segment of a chromosome is duplicated, leading to extra genetic material.
- Inversion: A segment of a chromosome is reversed in orientation.
- Translocation: A segment of one chromosome is transferred to another chromosome.

4. Gene Mutations:
- Gene mutations occur within a single gene and can affect protein function.
- Examples of gene mutations include:
- Base substitutions: Changes in a single nucleotide base.
- Frameshift mutations: Insertions or deletions that alter the reading frame of the genetic code.
Overall, mutations play a crucial role in genetic diversity and evolution but can also lead to genetic disorders and diseases. Understanding the different types of mutations is essential in studying their effects on organisms.
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