Which is correct sequence of events of inflammation or phagocytosis 1)...
Vasodilation is one of the earliest manifestations of acute inflammation. It refers to the widening of the blood vessels. Then leucocytes adheres to the vascular endothelium. The changes in the structure of microvascular emigrate the leucocytes from microcirculation followed by Chemotaxis, where by the cells move in response to chemical signals and the movement is known as diapediasis. Lastly is phagocytosis where the cell or phagocyte engulfs a solid particle to form an internal vesicle known as phagosome.
Thus, the correct answer is option (2) Vasodilation-> Adhesion->Diapediasis->Chemotaxis->Phagocytosis.
Which is correct sequence of events of inflammation or phagocytosis 1)...
Correct Sequence of Inflammation Events
The correct sequence of events in inflammation is outlined in option 4: vasodilation - adhesion - chemotaxis - diapedesis - phagocytosis. Here’s a breakdown of each step:
1. Vasodilation
- Definition: This is the widening of blood vessels.
- Purpose: It increases blood flow to the affected area, causing redness and heat.
2. Adhesion
- Definition: White blood cells (WBCs) adhere to the endothelial cells of blood vessels.
- Purpose: This is crucial for the WBCs to exit the bloodstream and enter the tissue.
3. Chemotaxis
- Definition: This is the movement of WBCs towards the site of inflammation in response to chemical signals.
- Purpose: Attracts immune cells to the site of injury or infection, guiding them to where they are needed.
4. Diapedesis
- Definition: The process by which WBCs squeeze through the gaps in the endothelial lining of blood vessels.
- Purpose: Allows WBCs to migrate into the tissue where they can act against pathogens.
5. Phagocytosis
- Definition: The process by which WBCs engulf and digest foreign particles, bacteria, or dead cells.
- Purpose: This is the final step where the immune cells eliminate pathogens and begin tissue repair.
Conclusion
Understanding the correct sequence of these events is vital for comprehending how the immune response operates during inflammation. Each step plays a critical role in ensuring effective healing and defense against infections.
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