Test for Cell Cycle and Cell Division

The cell cycle and cell division are essential processes that enable the growth and development of organisms. To understand these processes, various tests have been developed that help in studying the different stages of the cell cycle and cell division. Here are some of the tests for cell cycle and cell division:

1. Mitotic index test: This test measures the number of cells undergoing mitosis in a tissue sample. It is used to determine the rate of cell division in a tissue and is often used in cancer research.

2. BrdU incorporation test: This test measures the rate of DNA synthesis in cells. BrdU is a thymidine analogue that is incorporated into newly synthesized DNA during the S phase of the cell cycle. By measuring the amount of BrdU incorporated into cells, researchers can determine the rate of DNA synthesis.

3. Flow cytometry: This test measures the DNA content of cells as they pass through a flow cytometer. By analyzing the DNA content of cells, researchers can determine the different stages of the cell cycle that the cells are in.

4. Chromosome analysis: This test involves the staining and visualization of chromosomes in cells. By analyzing the number and structure of chromosomes, researchers can determine if there are any abnormalities that may affect the cell cycle and cell division.

5. Karyotyping: This test involves the visualization of the entire set of chromosomes in a cell. By analyzing the karyotype of a cell, researchers can determine if there are any chromosomal abnormalities that may affect the cell cycle and cell division.

Previous Year Questions (AIIMS, NEET, State PMT)

1. What is the mitotic index? How is it calculated? (NEET 2018)

2. What is the significance of BrdU incorporation test in cell cycle studies? (AIIMS 2019)

3. What is flow cytometry? How is it used to study the cell cycle? (NEET 2017)

4. What is the difference between chromosome analysis and karyotyping? (State PMT 2016)

In conclusion, the cell cycle and cell division are essential processes that enable the growth and development of organisms. To understand these processes, various tests have been developed, including the mitotic index test, BrdU incorporation test, flow cytometry, chromosome analysis, and karyotyping. These tests are often used in cancer research and other areas of biology to study the different stages of the cell cycle and cell division.

NEET & JEE PREPARATION SERIES | Complete MBBS, IT & Software Course | 5 docs, 2 tests - Awantika Gupta | EduRev