Directions: In the following questions a statement of assertion (A) i...
According to Chargaff's rule the DNA helix contains an equal molar ratio of A & T, G & C.... . This does not apply to RNA, as uracil is present in RNA instead of DNA. RNA contains ribose sugar in them.
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Directions: In the following questions a statement of assertion (A) i...
Assertion (A): Chargaff's rule is applicable to RNA.
Reason (R): RNA contains deoxyribose sugar in them.
The correct answer is option D, which states that Assertion (A) is false but Reason (R) is true.
Explanation:
Chargaff's Rule:
Chargaff's rule, also known as the base pairing rule, states that in DNA, the amount of adenine (A) is equal to the amount of thymine (T), and the amount of cytosine (C) is equal to the amount of guanine (G). This rule applies specifically to DNA and not to RNA.
RNA:
RNA (Ribonucleic acid) is a single-stranded nucleic acid molecule that plays a crucial role in the synthesis of proteins. It is composed of a chain of nucleotides, each containing a nitrogenous base (adenine, guanine, cytosine, or uracil), a ribose sugar, and a phosphate group.
Difference between DNA and RNA:
1. Sugar: DNA contains deoxyribose sugar, while RNA contains ribose sugar.
2. Bases: DNA has four bases - adenine (A), thymine (T), cytosine (C), and guanine (G). RNA also has adenine (A), cytosine (C), and guanine (G), but it replaces thymine (T) with uracil (U).
Analysis of the Assertion and Reason:
Assertion (A): Chargaff's rule is applicable to RNA.
This statement is false. Chargaff's rule is specifically applicable to DNA and its base pairing (A-T and C-G). RNA does not follow the same base pairing as DNA, as it contains uracil (U) instead of thymine (T).
Reason (R): RNA contains deoxyribose sugar in them.
This statement is true. RNA contains ribose sugar, not deoxyribose sugar. The deoxyribose sugar is specific to DNA, not RNA.
Conclusion:
Based on the analysis, it can be concluded that Assertion (A) is false because Chargaff's rule is not applicable to RNA. However, Reason (R) is true because RNA contains ribose sugar. Therefore, option D is the correct answer.
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