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Directions: In the following questions a statement of assertion (A) is followed by a statement of reason (R). Mark the correct choice as :
Assertion (A) : Primary transcripts in eukaryotes are non-functional.
Reason (R) : Methyl guanosine triphosphate isattached to 5’ – end of hnRNA.
  • a)
    Both assertion (A) and reason (R) are true and reason (R) is the correct explanation of assertion (A).
  • b)
    Both assertion (A) and reason (R) are true but reason (R) is not the correct explanation of assertion (A).
  • c)
    Assertion (A) is true but reason (R) is false.
  • d)
    Assertion (A) is false but reason (R) is true.
Correct answer is option 'B'. Can you explain this answer?
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Directions: In the following questions a statement of assertion (A) i...
Primary transcripts contains both introns and exon, in which introns are noncoding
parts.
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Directions: In the following questions a statement of assertion (A) i...
Assertion (A): Primary transcripts in eukaryotes are non-functional.
Reason (R): Methyl guanosine triphosphate is attached to the 5’ – end of hnRNA.

The correct answer is option B: Both assertion (A) and reason (R) are true but reason (R) is not the correct explanation of assertion (A).

Explanation:

Primary Transcripts in Eukaryotes:
- Primary transcripts, also known as heterogeneous nuclear RNA (hnRNA), are RNA molecules that are initially transcribed from DNA in the nucleus of eukaryotic cells.
- Primary transcripts undergo several modifications before they become functional mRNA molecules that can be translated into proteins.
- These modifications include the addition of a 5' cap and a poly-A tail, as well as the removal of introns through a process called splicing.

Methyl Guanosine Triphosphate (m7GTP) and hnRNA:
- Methyl guanosine triphosphate (m7GTP) is a modified nucleotide that is attached to the 5' end of hnRNA.
- This modification is known as the 5' cap and plays several important roles in the processing and stability of hnRNA.
- The 5' cap protects the RNA molecule from degradation by exonucleases and helps in the efficient export of hnRNA from the nucleus to the cytoplasm.
- It also plays a role in the initiation of translation by interacting with the translation initiation factors.

Non-functionality of Primary Transcripts:
- Primary transcripts, or hnRNA, are considered non-functional because they undergo several modifications before they can be translated into proteins.
- The addition of the 5' cap is one of these modifications and is essential for the processing and stability of hnRNA.
- However, the presence of the 5' cap alone does not make the primary transcript functional.
- The primary transcript still needs to undergo splicing to remove introns and the addition of a poly-A tail before it can be considered as mature mRNA.
- It is the mature mRNA molecules that are functional and can be translated into proteins.

Conclusion:
- In conclusion, while both the assertion and the reason are true, the reason does not provide a correct explanation for the non-functionality of primary transcripts in eukaryotes.
- The non-functionality of primary transcripts is due to the fact that they require additional modifications, such as splicing and the addition of a poly-A tail, before they can be considered as mature mRNA molecules.
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Directions: In the following questions a statement of assertion (A) is followed by a statement of reason (R). Mark the correct choice as :Assertion (A) : Primary transcripts in eukaryotes are non-functional.Reason (R) : Methyl guanosine triphosphate isattached to 5’ – end of hnRNA.a)Both assertion (A) and reason (R) are true and reason (R) is the correct explanation of assertion (A).b)Both assertion (A) and reason (R) are true but reason (R) is not the correct explanation of assertion (A).c)Assertion (A) is true but reason (R) is false.d)Assertion (A) is false but reason (R) is true.Correct answer is option 'B'. Can you explain this answer?
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Directions: In the following questions a statement of assertion (A) is followed by a statement of reason (R). Mark the correct choice as :Assertion (A) : Primary transcripts in eukaryotes are non-functional.Reason (R) : Methyl guanosine triphosphate isattached to 5’ – end of hnRNA.a)Both assertion (A) and reason (R) are true and reason (R) is the correct explanation of assertion (A).b)Both assertion (A) and reason (R) are true but reason (R) is not the correct explanation of assertion (A).c)Assertion (A) is true but reason (R) is false.d)Assertion (A) is false but reason (R) is true.Correct answer is option 'B'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about Directions: In the following questions a statement of assertion (A) is followed by a statement of reason (R). Mark the correct choice as :Assertion (A) : Primary transcripts in eukaryotes are non-functional.Reason (R) : Methyl guanosine triphosphate isattached to 5’ – end of hnRNA.a)Both assertion (A) and reason (R) are true and reason (R) is the correct explanation of assertion (A).b)Both assertion (A) and reason (R) are true but reason (R) is not the correct explanation of assertion (A).c)Assertion (A) is true but reason (R) is false.d)Assertion (A) is false but reason (R) is true.Correct answer is option 'B'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Directions: In the following questions a statement of assertion (A) is followed by a statement of reason (R). Mark the correct choice as :Assertion (A) : Primary transcripts in eukaryotes are non-functional.Reason (R) : Methyl guanosine triphosphate isattached to 5’ – end of hnRNA.a)Both assertion (A) and reason (R) are true and reason (R) is the correct explanation of assertion (A).b)Both assertion (A) and reason (R) are true but reason (R) is not the correct explanation of assertion (A).c)Assertion (A) is true but reason (R) is false.d)Assertion (A) is false but reason (R) is true.Correct answer is option 'B'. Can you explain this answer?.
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