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First reduction in pentose phosphate pathway is
  • a)
    Oxidation of 6-phosphogluconate
  • b)
    Oxidation of fructose 6-phosphate
  • c)
    Oxidation of glucose 6-phosphate
  • d)
    Oxidation of fructcose 5-phosphate
Correct answer is option 'C'. Can you explain this answer?
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First reduction in pentose phosphate pathway isa)Oxidation of 6-phosph...
PPP on the pentose phosphate pathway is an alternative pathway for the breakdown of glucose and is independent of glycolysis and Krebs cycle. This is the only process that helps in the formation of NADP. In this, 36 molecules of ATP are synthesized. This process starts with the first reduction of glucose 6 phosphates to 6-phosphogluconic acid.
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First reduction in pentose phosphate pathway isa)Oxidation of 6-phosph...
A group of structurally similar or dissimilar cells that perform a common function and have a common origin is called a tissue. A plant is made up of different kinds of tissues. The complex tissues are, however, composed of different kinds of cells and they perform different types of functions
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First reduction in pentose phosphate pathway isa)Oxidation of 6-phosph...
Explanation:

The pentose phosphate pathway (PPP), also known as the hexose monophosphate (HMP) shunt, is a metabolic pathway that generates NADPH and pentoses (5-carbon sugars) as intermediates. It is an alternative pathway to glycolysis for the metabolism of glucose.

Reduction in the Pentose Phosphate Pathway:

The reduction reactions in the pentose phosphate pathway involve the conversion of NADP+ (nicotinamide adenine dinucleotide phosphate) to NADPH (reduced form) and the production of pentose sugars.

Oxidation of Glucose 6-Phosphate:

The first reduction step in the pentose phosphate pathway occurs during the oxidation of glucose 6-phosphate. Glucose 6-phosphate is converted to 6-phosphogluconolactone by the enzyme glucose 6-phosphate dehydrogenase. This reaction generates NADPH as a byproduct.

Importance of NADPH:

NADPH is a crucial molecule in various biochemical reactions. It acts as a reducing agent, providing reducing equivalents for biosynthetic reactions, detoxification of reactive oxygen species (ROS), and maintenance of cellular redox balance. NADPH is required for the synthesis of fatty acids, cholesterol, and nucleotides.

Other Steps in the Pentose Phosphate Pathway:

After the oxidation of glucose 6-phosphate, the 6-phosphogluconolactone is hydrolyzed by the enzyme 6-phosphogluconolactonase to form 6-phosphogluconate. This reaction does not involve any reduction or oxidation.

Conclusion:

The first reduction step in the pentose phosphate pathway occurs during the oxidation of glucose 6-phosphate, which generates NADPH. Therefore, the correct answer is option C, oxidation of glucose 6-phosphate.
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Read the passage given below and answer the following questions:Adenosine triphosphate (ATP) is the energy carrying molecule found in the cells of all living things. ATP captures chemical energy obtained from the breakdown of food molecules and releases it to fuel other cellular processes. ATP is a nucleotide that consists of three main structures: the nitrogenous base, adenine; the sugar, ribose; and a chain of three phosphate groups bound to ribose. The phosphate tail of ATP is the actual power source which the cell taps. Available energy is contained in the bonds between the phosphates and is released when they are broken, which occurs through the addition of a water molecule (a process called hydrolysis). Usually only the outer phosphate is removed from ATP to yield energy; when this occurs ATP is converted to adenosine diphosphate (ADP), the form of the nucleotide having only two phosphates.The importance of ATP (adenosine triphosphat e) as the main source of chemical energy in living matter and its involvement in cellular processes has long been recognized. The primary mechanism whereby higher organisms, including humans, generate ATP is through mitochondrial oxidative phosphorylation. For the majority of organs, the main metabolic fuel is glucose, which in the presence of oxygen undergoes complete combustion to CO2 and H2O: C6H12O6 + 6O2 → 6O2 + 6H2O + energyThe free energy (ΔG) liberated in this exergonic (ΔG is negative) reaction is partially trapped as ATP in two consecutive processes: glycolysis (cytosol) and oxidative phosphorylation (mitochondri

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First reduction in pentose phosphate pathway isa)Oxidation of 6-phosphogluconateb)Oxidation of fructose 6-phosphatec)Oxidation of glucose 6-phosphated)Oxidation of fructcose 5-phosphateCorrect answer is option 'C'. Can you explain this answer?
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First reduction in pentose phosphate pathway isa)Oxidation of 6-phosphogluconateb)Oxidation of fructose 6-phosphatec)Oxidation of glucose 6-phosphated)Oxidation of fructcose 5-phosphateCorrect answer is option 'C'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about First reduction in pentose phosphate pathway isa)Oxidation of 6-phosphogluconateb)Oxidation of fructose 6-phosphatec)Oxidation of glucose 6-phosphated)Oxidation of fructcose 5-phosphateCorrect answer is option 'C'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for First reduction in pentose phosphate pathway isa)Oxidation of 6-phosphogluconateb)Oxidation of fructose 6-phosphatec)Oxidation of glucose 6-phosphated)Oxidation of fructcose 5-phosphateCorrect answer is option 'C'. Can you explain this answer?.
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