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Which of the following statements is not correct?    [2020]
  • a)
    The functional insulin has A and B chains linked together by hydrogen bonds.
  • b)
    Genetically engineered insulin is produced in E-Coli.
  • c)
    In man insulin is synthesised as a proinsulin.
  • d)
    The proinsulin has an extra peptide called C-peptide.
Correct answer is option 'A'. Can you explain this answer?
Verified Answer
Which of the following statements is not correct? [2020]a)The functio...
The functional insulin molecule has two chains A and chain B, that are linked together by disulphide bridges and not hydrogen bonds.
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Most Upvoted Answer
Which of the following statements is not correct? [2020]a)The functio...
Insulin is a hormone produced by the pancreas that regulates blood sugar levels in the body. The given statements are related to the structure and production of insulin.

Explanation:

A) The functional insulin has A and B chains linked together by hydrogen bonds. This statement is not correct because the A and B chains of insulin are linked together by disulfide bonds, not hydrogen bonds.

B) Genetically engineered insulin is produced in E-Coli. This statement is correct. Recombinant DNA technology has been used to produce insulin in bacteria, such as E. coli, which can be grown in large quantities and can produce human insulin.

C) In man insulin is synthesized as a proinsulin. This statement is correct. Insulin is initially produced as a larger precursor molecule called proinsulin, which is then processed into insulin by cleaving off the C-peptide.

D) The proinsulin has an extra peptide called C-peptide. This statement is correct. Proinsulin consists of three parts: the A chain, the B chain, and the C-peptide. During insulin synthesis, proinsulin is cleaved, and the C-peptide is removed, leaving the A and B chains linked by disulfide bonds to form insulin.

Therefore, the correct answer is option A.
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Which of the following statements is not correct? [2020]a)The functional insulin has A and B chains linked together by hydrogen bonds.b)Genetically engineered insulin is produced in E-Coli.c)In man insulin is synthesised as a proinsulin.d)The proinsulin has an extra peptide called C-peptide.Correct answer is option 'A'. Can you explain this answer?
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