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The signal transduction of steroid hormone across cell is through
- a)binding of hormone to the cytoplasmic receptor and the complex binds to hormone response element on DNA within promoter DNA
- b)binding of hormone to the transmembrane receptor which initiates the production of second messenger that activates enzymes which further activates transcription factors
- c)binding of hormone to the transmembrane receptor which diffuse inside the cell cytoplasm and then activates the enzyme necessary for the activation of transcription factors
- d)binding of hormone to the cytoplasmic receptor that initiates the production of second messenger which activates enzymes that further activates transcription factors
Correct answer is option 'A'. Can you explain this answer?
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The signal transduction of steroid hormone across cell is througha)bin...
Steroid hormones, being hydrophobic molecules, diffuse freely into all cells and act within the cell. Steroid hormones enter the cytoplasm of a target cell and bind with specific receptor proteins (mobile). Hormone-receptor complex then diffuses into nucleus and activates specific genes to form a new protein. This protein carries out the specific response for a particular steroid hormone.
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The signal transduction of steroid hormone across cell is througha)bin...
The Mechanism of Signal Transduction of Steroid Hormones Across Cells
Steroid hormones are lipophilic molecules that can easily penetrate the cell membrane and bind to specific cytoplasmic or nuclear receptors. The signal transduction of steroid hormones across cells is through a series of steps that ultimately activate gene expression.
Hormone Binding to Cytoplasmic Receptor
The first step in signal transduction of steroid hormones is the binding of hormone to the specific cytoplasmic receptor. This binding causes a conformational change in the receptor which leads to the formation of a hormone-receptor complex.
Hormone Response Element Binding
The hormone-receptor complex then translocates to the nucleus and binds to specific hormone response elements (HREs) on the DNA within the promoter region of the target gene. This binding initiates the recruitment of coactivators and the assembly of the transcriptional complex at the promoter region.
Activation of Gene Expression
The transcriptional complex then activates the transcription of the target gene, which leads to the production of mRNA. This mRNA is then translated into a functional protein that mediates the biological effects of the steroid hormone.
Conclusion
In summary, the signal transduction of steroid hormones across cells is a complex process that involves the binding of hormone to specific cytoplasmic or nuclear receptors, the translocation of the hormone-receptor complex to the nucleus, the binding of the complex to HREs on the DNA, and the activation of gene expression. This process ultimately leads to the production of functional proteins that mediate the biological effects of the steroid hormone.
Steroid hormones are lipophilic molecules that can easily penetrate the cell membrane and bind to specific cytoplasmic or nuclear receptors. The signal transduction of steroid hormones across cells is through a series of steps that ultimately activate gene expression.
Hormone Binding to Cytoplasmic Receptor
The first step in signal transduction of steroid hormones is the binding of hormone to the specific cytoplasmic receptor. This binding causes a conformational change in the receptor which leads to the formation of a hormone-receptor complex.
Hormone Response Element Binding
The hormone-receptor complex then translocates to the nucleus and binds to specific hormone response elements (HREs) on the DNA within the promoter region of the target gene. This binding initiates the recruitment of coactivators and the assembly of the transcriptional complex at the promoter region.
Activation of Gene Expression
The transcriptional complex then activates the transcription of the target gene, which leads to the production of mRNA. This mRNA is then translated into a functional protein that mediates the biological effects of the steroid hormone.
Conclusion
In summary, the signal transduction of steroid hormones across cells is a complex process that involves the binding of hormone to specific cytoplasmic or nuclear receptors, the translocation of the hormone-receptor complex to the nucleus, the binding of the complex to HREs on the DNA, and the activation of gene expression. This process ultimately leads to the production of functional proteins that mediate the biological effects of the steroid hormone.
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The signal transduction of steroid hormone across cell is througha)binding of hormone to the cytoplasmic receptor and the complex binds to hormone response element on DNA within promoter DNAb)binding of hormone to the transmembrane receptor which initiates the production of second messenger that activates enzymes which further activates transcription factorsc)binding of hormone to the transmembrane receptor which diffuse inside the cell cytoplasm and then activates the enzyme necessary for the activation of transcription factorsd)binding of hormone to the cytoplasmic receptor that initiates the production of second messenger which activates enzymes that further activates transcription factorsCorrect answer is option 'A'. Can you explain this answer?
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The signal transduction of steroid hormone across cell is througha)binding of hormone to the cytoplasmic receptor and the complex binds to hormone response element on DNA within promoter DNAb)binding of hormone to the transmembrane receptor which initiates the production of second messenger that activates enzymes which further activates transcription factorsc)binding of hormone to the transmembrane receptor which diffuse inside the cell cytoplasm and then activates the enzyme necessary for the activation of transcription factorsd)binding of hormone to the cytoplasmic receptor that initiates the production of second messenger which activates enzymes that further activates transcription factorsCorrect answer is option 'A'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about The signal transduction of steroid hormone across cell is througha)binding of hormone to the cytoplasmic receptor and the complex binds to hormone response element on DNA within promoter DNAb)binding of hormone to the transmembrane receptor which initiates the production of second messenger that activates enzymes which further activates transcription factorsc)binding of hormone to the transmembrane receptor which diffuse inside the cell cytoplasm and then activates the enzyme necessary for the activation of transcription factorsd)binding of hormone to the cytoplasmic receptor that initiates the production of second messenger which activates enzymes that further activates transcription factorsCorrect answer is option 'A'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for The signal transduction of steroid hormone across cell is througha)binding of hormone to the cytoplasmic receptor and the complex binds to hormone response element on DNA within promoter DNAb)binding of hormone to the transmembrane receptor which initiates the production of second messenger that activates enzymes which further activates transcription factorsc)binding of hormone to the transmembrane receptor which diffuse inside the cell cytoplasm and then activates the enzyme necessary for the activation of transcription factorsd)binding of hormone to the cytoplasmic receptor that initiates the production of second messenger which activates enzymes that further activates transcription factorsCorrect answer is option 'A'. Can you explain this answer?.
The signal transduction of steroid hormone across cell is througha)binding of hormone to the cytoplasmic receptor and the complex binds to hormone response element on DNA within promoter DNAb)binding of hormone to the transmembrane receptor which initiates the production of second messenger that activates enzymes which further activates transcription factorsc)binding of hormone to the transmembrane receptor which diffuse inside the cell cytoplasm and then activates the enzyme necessary for the activation of transcription factorsd)binding of hormone to the cytoplasmic receptor that initiates the production of second messenger which activates enzymes that further activates transcription factorsCorrect answer is option 'A'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about The signal transduction of steroid hormone across cell is througha)binding of hormone to the cytoplasmic receptor and the complex binds to hormone response element on DNA within promoter DNAb)binding of hormone to the transmembrane receptor which initiates the production of second messenger that activates enzymes which further activates transcription factorsc)binding of hormone to the transmembrane receptor which diffuse inside the cell cytoplasm and then activates the enzyme necessary for the activation of transcription factorsd)binding of hormone to the cytoplasmic receptor that initiates the production of second messenger which activates enzymes that further activates transcription factorsCorrect answer is option 'A'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for The signal transduction of steroid hormone across cell is througha)binding of hormone to the cytoplasmic receptor and the complex binds to hormone response element on DNA within promoter DNAb)binding of hormone to the transmembrane receptor which initiates the production of second messenger that activates enzymes which further activates transcription factorsc)binding of hormone to the transmembrane receptor which diffuse inside the cell cytoplasm and then activates the enzyme necessary for the activation of transcription factorsd)binding of hormone to the cytoplasmic receptor that initiates the production of second messenger which activates enzymes that further activates transcription factorsCorrect answer is option 'A'. Can you explain this answer?.
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