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What would happen, if in a gene encoding a polypeptide of 50 amino acids, 25th codon (UAU) is mutated to UAA?
  • a)
    A polypeptide of 49 amino acids will be formed
  • b)
    A polypeptide of 25 amino acids will be formed
  • c)
    A polypeptide of 24 amino acids will be formed
  • d)
    Two polypeptides of 24 and 25 amino acids will be formed
Correct answer is option 'C'. Can you explain this answer?
Verified Answer
What would happen, if in a gene encoding a polypeptide of 50 amino aci...
UAA is a nonsense codon. It signals for polypeptide chain termination. Hence, only 24 amino acids chain will be formed.
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What would happen, if in a gene encoding a polypeptide of 50 amino aci...
Introduction:
The given question states that there is a mutation in the 25th codon (UAU to UAA) of a gene encoding a polypeptide of 50 amino acids. We need to determine the effect of this mutation on the resulting polypeptide.

Explanation:
To understand the effect of the mutation, we need to consider the role of codons in protein synthesis. Codons are three-nucleotide sequences on mRNA that correspond to specific amino acids. During translation, the ribosome reads the codons and assembles the corresponding amino acids into a polypeptide chain.

Normal codon:
The normal codon at the 25th position is UAU, which codes for the amino acid tyrosine. This means that during translation, a tyrosine amino acid would be incorporated into the growing polypeptide chain at this position.

Mutated codon:
The mutated codon at the 25th position is UAA. This codon is a stop codon, also known as termination codon. Stop codons do not code for any amino acid but instead signal the end of translation. When a stop codon is encountered, the ribosome releases the polypeptide chain, and the translation process is terminated.

Effect of the mutation:
Since the mutation changes the codon at the 25th position from UAU (tyrosine) to UAA (stop codon), the translation process would be prematurely terminated at this point. As a result, the polypeptide chain would be shorter than the original length.

Length of the resulting polypeptide:
The original gene encodes a polypeptide of 50 amino acids. However, due to the premature termination caused by the mutation, the resulting polypeptide would be shorter.

To determine the length of the resulting polypeptide, we need to count the number of amino acids incorporated before the mutation occurs. In this case, the mutation occurs at the 25th codon, which means that 24 amino acids would have been incorporated before the translation is prematurely terminated.

Therefore, the correct answer is option c) A polypeptide of 24 amino acids will be formed.
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What would happen, if in a gene encoding a polypeptide of 50 amino acids, 25th codon (UAU) is mutated to UAA?a)A polypeptide of 49 amino acids will be formedb)A polypeptide of 25 amino acids will be formedc)A polypeptide of 24 amino acids will be formedd)Two polypeptides of 24 and 25 amino acids will be formedCorrect answer is option 'C'. Can you explain this answer?
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What would happen, if in a gene encoding a polypeptide of 50 amino acids, 25th codon (UAU) is mutated to UAA?a)A polypeptide of 49 amino acids will be formedb)A polypeptide of 25 amino acids will be formedc)A polypeptide of 24 amino acids will be formedd)Two polypeptides of 24 and 25 amino acids will be formedCorrect answer is option 'C'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about What would happen, if in a gene encoding a polypeptide of 50 amino acids, 25th codon (UAU) is mutated to UAA?a)A polypeptide of 49 amino acids will be formedb)A polypeptide of 25 amino acids will be formedc)A polypeptide of 24 amino acids will be formedd)Two polypeptides of 24 and 25 amino acids will be formedCorrect answer is option 'C'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for What would happen, if in a gene encoding a polypeptide of 50 amino acids, 25th codon (UAU) is mutated to UAA?a)A polypeptide of 49 amino acids will be formedb)A polypeptide of 25 amino acids will be formedc)A polypeptide of 24 amino acids will be formedd)Two polypeptides of 24 and 25 amino acids will be formedCorrect answer is option 'C'. Can you explain this answer?.
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