The cells that do not divide further, exit G1 phase to enter an inacti...
The phase in which cells fail to divide further (do not enter S- phase after G1 -phase) and undergo differentiation is known as G0 phase or quiescent stage. It occurs due to non availability of mitogen and energy rich compounds. The cells remain metabolically active, grow in size and differentiate for particular function after attaining a particular shape.
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The cells that do not divide further, exit G1 phase to enter an inacti...
Explanation:
The cell cycle is a series of events that take place in a cell, leading to its division and the production of two daughter cells. It consists of four main phases: G1 phase, S phase, G2 phase, and M phase.
During the G1 phase, the cell grows and carries out its normal functions. At the end of the G1 phase, the cell undergoes a checkpoint called the restriction point, which determines whether the cell will continue with the cell cycle or exit into a non-dividing state called the G0 phase.
G0 phase:
The G0 phase is an inactive stage of the cell cycle that occurs when cells exit G1 phase but do not proceed to the S phase to replicate their DNA and divide further. Cells in the G0 phase are considered to be temporarily or permanently in a resting state. They may remain in this stage for an extended period of time or indefinitely.
Characteristics of cells in the G0 phase:
- Cells in the G0 phase are metabolically active but do not actively divide.
- They may resume the cell cycle and re-enter G1 phase under certain conditions, such as in response to growth signals or tissue repair.
- Some cells, such as mature nerve cells and muscle cells, enter a permanent G0 phase and do not divide further.
Importance of the G0 phase:
The G0 phase allows cells to temporarily or permanently exit the cell cycle. This is important for various reasons:
- It allows cells to differentiate and acquire specialized functions.
- It maintains a balance between cell division and cell differentiation.
- It prevents uncontrolled cell proliferation and the formation of tumors.
Conclusion:
Cells that do not proceed to the S phase and divide further exit the G1 phase to enter the G0 phase, an inactive stage of the cell cycle. The G0 phase allows cells to temporarily or permanently remain in a resting state, providing balance and control in cell division and allowing for cellular differentiation and specialized functions.
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