Read the statements:(1) IgE antibodies are produced in an allergic re...
Explanation:
The correct answer is option D, which states that statements (1) and (4) are correct.
Statement 1: IgE antibodies are produced in an allergic reaction.
This statement is correct. IgE antibodies are a type of immunoglobulin produced by B-lymphocytes in response to an allergic reaction. When the body is exposed to an allergen, such as pollen or dust mites, it triggers an immune response. B-lymphocytes recognize the allergen and produce IgE antibodies specific to that allergen. These IgE antibodies then bind to mast cells and basophils, which are immune cells involved in allergic reactions. The binding of IgE antibodies to these cells triggers the release of inflammatory mediators like histamine, leading to symptoms of an allergic reaction.
Statement 4: Spleen is a secondary lymphoid organ.
This statement is also correct. The spleen is an organ located in the upper left part of the abdomen. It is part of the lymphatic system and functions as a secondary lymphoid organ. Lymphoid organs are sites where immune responses occur. The spleen filters the blood and removes old or damaged red blood cells, as well as foreign particles, bacteria, and other pathogens. It also plays a role in the immune response by producing antibodies and immune cells. B-lymphocytes, T-lymphocytes, and antigen-presenting cells are all found in the spleen and contribute to immune surveillance and response.
Statement 2: B-lymphocytes mediate cell-mediated immunity.
This statement is incorrect. B-lymphocytes are involved in the production of antibodies and are responsible for humoral immunity, not cell-mediated immunity. Cell-mediated immunity is primarily mediated by T-lymphocytes, specifically cytotoxic T cells and helper T cells. These cells directly attack and kill infected cells or help in the activation of other immune cells.
Statement 3: The yellowish fluid colostrum has abundant IgE antibodies.
This statement is incorrect. Colostrum is the first milk produced by mammals, including humans, in the initial days after giving birth. It is rich in antibodies, particularly IgA antibodies, which provide passive immunity to the newborn. IgE antibodies are not typically found in colostrum.
To summarize, the correct statements are (1) IgE antibodies are produced in an allergic reaction, and (4) Spleen is a secondary lymphoid organ. Statement (2) is incorrect, and statement (3) is incorrect.
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