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Identify the reaction from following which involves protection and deprotection of functional group A) m- Hydroxybenzaldehyde to m- Hydroxy benzoic acid B). Aniline to p- bromoaniline C). Aniline to p-nitroaniline D). All of these?
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Identify the reaction from following which involves protection and dep...
Protection and Deprotection Reactions in Organic Chemistry
m-Hydroxybenzaldehyde to m-Hydroxybenzoic Acid:
- Protection: The hydroxyl group (-OH) of m-hydroxybenzaldehyde is protected by converting it into an ester using a carboxylic acid anhydride and a catalyst. This reaction is called acetylation.
- Deprotection: The ester group is then deprotected by hydrolysis using an aqueous solution of sodium hydroxide, which converts it back to the original hydroxyl group as m-hydroxybenzoic acid.
Aniline to p-Bromoaniline:
- Protection: The amino group (-NH2) of aniline is protected by converting it into an amide using a carboxylic acid anhydride and a catalyst. This reaction is called amidation.
- Deprotection: The amide group is then deprotected by hydrolysis using an acidic solution of hydrobromic acid, which converts it back to the original amino group as p-bromoaniline.
Aniline to p-Nitroaniline:
- Protection: The amino group (-NH2) of aniline is protected by converting it into an amide using a carboxylic acid anhydride and a catalyst. This reaction is called amidation.
- Deprotection: The amide group is then deprotected by reduction using a reducing agent such as tin and hydrochloric acid, which converts it back to the original amino group as p-nitroaniline.
All of these:
All of the reactions mentioned above involve protection and deprotection of functional groups in organic chemistry. These reactions are commonly used in organic synthesis to selectively modify specific functional groups while leaving other groups untouched.
m-Hydroxybenzaldehyde to m-Hydroxybenzoic Acid:
- Protection: The hydroxyl group (-OH) of m-hydroxybenzaldehyde is protected by converting it into an ester using a carboxylic acid anhydride and a catalyst. This reaction is called acetylation.
- Deprotection: The ester group is then deprotected by hydrolysis using an aqueous solution of sodium hydroxide, which converts it back to the original hydroxyl group as m-hydroxybenzoic acid.
Aniline to p-Bromoaniline:
- Protection: The amino group (-NH2) of aniline is protected by converting it into an amide using a carboxylic acid anhydride and a catalyst. This reaction is called amidation.
- Deprotection: The amide group is then deprotected by hydrolysis using an acidic solution of hydrobromic acid, which converts it back to the original amino group as p-bromoaniline.
Aniline to p-Nitroaniline:
- Protection: The amino group (-NH2) of aniline is protected by converting it into an amide using a carboxylic acid anhydride and a catalyst. This reaction is called amidation.
- Deprotection: The amide group is then deprotected by reduction using a reducing agent such as tin and hydrochloric acid, which converts it back to the original amino group as p-nitroaniline.
All of these:
All of the reactions mentioned above involve protection and deprotection of functional groups in organic chemistry. These reactions are commonly used in organic synthesis to selectively modify specific functional groups while leaving other groups untouched.
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Identify the reaction from following which involves protection and deprotection of functional group A) m- Hydroxybenzaldehyde to m- Hydroxy benzoic acid B). Aniline to p- bromoaniline C). Aniline to p-nitroaniline D). All of these?
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Identify the reaction from following which involves protection and deprotection of functional group A) m- Hydroxybenzaldehyde to m- Hydroxy benzoic acid B). Aniline to p- bromoaniline C). Aniline to p-nitroaniline D). All of these? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about Identify the reaction from following which involves protection and deprotection of functional group A) m- Hydroxybenzaldehyde to m- Hydroxy benzoic acid B). Aniline to p- bromoaniline C). Aniline to p-nitroaniline D). All of these? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Identify the reaction from following which involves protection and deprotection of functional group A) m- Hydroxybenzaldehyde to m- Hydroxy benzoic acid B). Aniline to p- bromoaniline C). Aniline to p-nitroaniline D). All of these?.
Identify the reaction from following which involves protection and deprotection of functional group A) m- Hydroxybenzaldehyde to m- Hydroxy benzoic acid B). Aniline to p- bromoaniline C). Aniline to p-nitroaniline D). All of these? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about Identify the reaction from following which involves protection and deprotection of functional group A) m- Hydroxybenzaldehyde to m- Hydroxy benzoic acid B). Aniline to p- bromoaniline C). Aniline to p-nitroaniline D). All of these? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Identify the reaction from following which involves protection and deprotection of functional group A) m- Hydroxybenzaldehyde to m- Hydroxy benzoic acid B). Aniline to p- bromoaniline C). Aniline to p-nitroaniline D). All of these?.
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