Increased Glomerular Filtration Rate (GFR) and Nephric Filtrate Formation

Introduction:
The glomerular filtration rate (GFR) is a measure of the volume of fluid filtered through the glomeruli of the kidneys per unit of time. It is an important indicator of kidney function. In this scenario, the GFR is increased by 20%, and we need to determine the amount of nephric filtrate formed in 24 hours assuming reabsorption remains unchanged.

Understanding Glomerular Filtration:
The glomerular filtration occurs in the renal corpuscle, which consists of the glomerulus and Bowman's capsule. The glomerulus is a network of capillaries that acts as a filtration barrier, while Bowman's capsule surrounds the glomerulus and collects the filtrate.

Factors Affecting GFR:
The GFR is influenced by several factors, including the permeability of the filtration barrier, the hydrostatic pressure in the glomerulus, and the oncotic pressure in the blood vessels. Changes in these factors can affect the GFR.

Effect of Increased GFR:
When the GFR increases, more fluid is filtered through the glomeruli. In this scenario, the GFR is increased by 20%. Consequently, the amount of nephric filtrate formed in 24 hours will also increase.

Calculating Nephric Filtrate Formation:
To determine the amount of nephric filtrate formed in 24 hours, we need to multiply the GFR by the time interval (24 hours). Assuming the GFR before the increase is "x," the GFR after the increase will be 1.2x.

Therefore, the amount of nephric filtrate formed in 24 hours can be calculated as follows:
Nephric Filtrate Formation = GFR * Time Interval

Substituting the values:
Nephric Filtrate Formation = (1.2x) * 24

Conclusion:
In conclusion, if the glomerular filtration rate (GFR) is increased by 20% and reabsorption remains unchanged, the amount of nephric filtrate formed in 24 hours will increase by the same percentage. The calculation depends on the initial GFR value (x), with the new GFR being 1.2x. The amount of nephric filtrate can be determined by multiplying the GFR by the time interval (24 hours).