Which of the following reactions will not result in the formation of ...
Phenol has active (acidic) hydrogen so it reacts with CH
3Mgl to give CH
4, and not anisole
C6H5OH + CH3MgI------> CH4 + C6H5OMgI
Which of the following reactions will not result in the formation of ...
Reaction options:
a) Phenol + dimethyl sulphate in presence of a base.
b) Sodium phenoxide + methyl iodide.
c) Diazomethane + phenol.
d) Methylmagnesium iodide + phenol.
Explanation:
a) Phenol + dimethyl sulphate in presence of a base:
This reaction is known as the Williamson ether synthesis and is used to form ethers. In this case, phenol reacts with dimethyl sulphate in the presence of a base to form anisole. The base deprotonates phenol to generate phenoxide ion, which then reacts with dimethyl sulfate to give anisole. Therefore, this reaction does result in the formation of anisole.
b) Sodium phenoxide + methyl iodide:
This reaction is also known as the Williamson ether synthesis. Sodium phenoxide is a strong base and it deprotonates phenol to generate phenoxide ion. However, in this reaction, the phenoxide ion does not react with methyl iodide to form anisole. Instead, it reacts with methyl iodide to form o-methylphenol. Therefore, this reaction does not result in the formation of anisole.
c) Diazomethane + phenol:
This reaction involves the reaction of diazomethane with phenol. Diazomethane is a highly reactive and potentially explosive compound. The reaction of diazomethane with phenol is not a known reaction and is unlikely to occur. Therefore, this reaction does not result in the formation of anisole.
d) Methylmagnesium iodide + phenol:
This reaction is known as the Grignard reaction and is used to form alcohols. In this case, methylmagnesium iodide reacts with phenol to form a tertiary alcohol. The reaction does not result in the formation of anisole. Therefore, the correct answer is option 'D'.
Conclusion:
Among the given reaction options, the reaction of methylmagnesium iodide with phenol (option 'D') does not result in the formation of anisole.
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