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At which of the given step of TCA cycle CO2 is released along with reduction of NAD+?
- a)Oxaloacetic acid → α-Ketoglutaric acid
- b)Malic acid → Oxaloacetic acid
- c)Pyruvic acid → Acetyl CoA
- d)α-KGA → Succinyl CoA
Correct answer is option 'D'. Can you explain this answer?
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At which of the given step of TCA cycle CO2 is released along with re...
Step of TCA cycle where CO2 is released along with reduction of NAD+
CO2 release and reduction of NAD+ occur during the conversion of alpha-ketoglutarate (α-KGA) to succinyl CoA in the TCA cycle.
- Alpha-Ketoglutarate to Succinyl CoA:
During this step of the TCA cycle, alpha-ketoglutarate is converted to succinyl CoA with the release of CO2. This reaction is catalyzed by the enzyme alpha-ketoglutarate dehydrogenase complex. At the same time, NAD+ is reduced to NADH.
This step is crucial in the TCA cycle as it helps in the generation of reducing equivalents in the form of NADH and FADH2, which are essential for ATP production in the electron transport chain.
Therefore, the correct answer is option D - alpha-ketoglutarate to succinyl CoA.
CO2 release and reduction of NAD+ occur during the conversion of alpha-ketoglutarate (α-KGA) to succinyl CoA in the TCA cycle.
- Alpha-Ketoglutarate to Succinyl CoA:
During this step of the TCA cycle, alpha-ketoglutarate is converted to succinyl CoA with the release of CO2. This reaction is catalyzed by the enzyme alpha-ketoglutarate dehydrogenase complex. At the same time, NAD+ is reduced to NADH.
This step is crucial in the TCA cycle as it helps in the generation of reducing equivalents in the form of NADH and FADH2, which are essential for ATP production in the electron transport chain.
Therefore, the correct answer is option D - alpha-ketoglutarate to succinyl CoA.
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At which of the given step of TCA cycle CO2 is released along with reduction of NAD+?a)Oxaloacetic acid → α-Ketoglutaric acidb)Malic acid → Oxaloacetic acidc)Pyruvic acid → Acetyl CoAd)α-KGA → Succinyl CoACorrect answer is option 'D'. Can you explain this answer?
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