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All are correct with respect to the Human Genome Project, except
  • a)
    Its goal was to determine the sequence of the 3 billion chemical base pairs that make up human DNA
  • b)
    Caenorhabditis elegans and Arabidopsis are the non-human model organisms, that have been sequenced
  • c)
    The sequence of chromosome-1 was completed only in May 2006, this was the last of the 24 human chromosomes to be sequenced
  • d)
    14 million locations are identified in humans with single base DNA differences
Correct answer is option 'D'. Can you explain this answer?
Most Upvoted Answer
All are correct with respect to the Human Genome Project, excepta)Its...
Explanation:

The correct answer is option D, which states that 14 million locations are identified in humans with single base DNA differences.

Human Genome Project:

The Human Genome Project (HGP) was an international research effort that aimed to map and sequence the entire human genome. It started in 1990 and was completed in 2003. The project had several goals, including determining the sequence of the 3 billion chemical base pairs that make up human DNA, identifying all the genes in the human genome, and understanding the function of these genes.

Key Points:

a) Goal of the Human Genome Project:
- The goal of the Human Genome Project was to determine the sequence of the 3 billion chemical base pairs that make up human DNA.
- This involved identifying the order of the four nucleotide bases - adenine (A), thymine (T), cytosine (C), and guanine (G) - in the DNA molecule.

b) Non-human model organisms:
- Caenorhabditis elegans and Arabidopsis are two non-human model organisms that have been sequenced.
- These organisms were chosen because they have relatively small genomes and are widely used in biological research.

c) Completion of chromosome-1 sequencing:
- The sequencing of the human genome was a complex and time-consuming process.
- The sequence of chromosome-1, which is the largest human chromosome, was completed in May 2006.
- This was the last of the 24 human chromosomes to be sequenced.

d) Identification of single base DNA differences:
- The Human Genome Project identified single base DNA differences, also known as single nucleotide polymorphisms (SNPs), in the human genome.
- SNPs are variations in a single nucleotide base at a specific location in the genome.
- These variations can have important implications for human health and disease.
- However, the number of identified SNPs is much larger than 14 million. The actual number is estimated to be around 80 million.

Conclusion:

In summary, all the given statements about the Human Genome Project are correct except for option D, which states that 14 million locations are identified in humans with single base DNA differences. The actual number of identified SNPs is estimated to be around 80 million.
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Community Answer
All are correct with respect to the Human Genome Project, excepta)Its...
The major findings of human genome project (HGP) are:
  1. The human genome contains 3164.7 million bp.
  2. The average gene consists of 3000 bases, but sizes vary greatly, with the largest known human gene is dystrophin with 2.4 million bases.
  3. Only less than 2 % of the genome codes for proteins.
  4. Chromosome 1 has maximum number of genes (2968), and the Y has the fewest (231).
  5. The total number of genes is estimated at 30,000–much lower than previous estimates of 80,000 to 1,40,000 genes. Almost all (99.9 per cent) nucleotide bases are exactly the same in all people.
  6. The functions are unknown for over 50 per cent of the discovered genes.
  7. Scientists have identified about 1.4 million locations where single-base DNA differences (SNPs – single nucleotide polymorphism) occur in humans. This information helps the processes of finding chromosomal locations for disease-associated sequences and tracing human history.
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All are correct with respect to the Human Genome Project, excepta)Its goal was to determine the sequence of the 3 billion chemical base pairs that make up human DNAb)Caenorhabditis elegans and Arabidopsis are the non-human model organisms, that have been sequencedc)The sequence of chromosome-1 was completed only in May 2006, this was the last of the 24 human chromosomes to be sequencedd)14 million locations are identified in humans with single base DNA differencesCorrect answer is option 'D'. Can you explain this answer?
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