Which of the following types of disorder is transferred from a phenot...
Sex-linked recessive inheritance refers to genetic conditions associated with mutations in genes on the X chromosome. A male carrying such a mutation will be affected, because he carries only one X chromosome. A female carrying a mutation in one gene, with a normal gene on the other X chromosome, is generally unaffected. Sex-linked recessive is the type of disorder transferred from a phenotypically normal, but carrier female to only some of the male progeny.
Which of the following types of disorder is transferred from a phenot...
Sex-linked recessive disorder transmission:
When a female carries a recessive allele for a disorder on one of the sex chromosomes (X-linked recessive), she is typically phenotypically normal. However, when she passes on this allele to her offspring, only some of the male progeny may express the disorder, while females are less likely to be affected.
Explanation:
- In humans, males have one X and one Y chromosome, while females have two X chromosomes.
- If a female is a carrier for an X-linked recessive disorder, she has one normal X chromosome and one X chromosome carrying the recessive allele.
- When she passes on these chromosomes to her offspring, males have a 50% chance of inheriting the X chromosome with the recessive allele, leading to the expression of the disorder.
- Females, on the other hand, need to inherit the recessive allele from both parents to express the disorder, making them less likely to be affected.
- This pattern of inheritance results in the transmission of the disorder from a phenotypically normal carrier female to only some of the male progeny.
Therefore, the correct answer is option 'D) Sex-linked recessive'.
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