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Which step of glycolysis involves the formation of NADH + H+?
- a)Conversion of glucose to glucose-6-phosphate
- b)Conversion of fructose-6-phosphate to fructose 1, 6-bisphosphate
- c)Conversion of 3-phosphoglyceraldehyde to 1, 3-bisphosphoglycerate
- d)Conversion of phosphoenolpyruvate (PEP) to pyruvic acid
Correct answer is option 'C'. Can you explain this answer?
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Which step of glycolysis involves the formation of NADH + H+?a)Convers...
The correct answer is option C) Conversion of 3-phosphoglyceraldehyde to 1, 3-bisphosphoglycerate.
Glycolysis is the metabolic pathway that converts glucose into pyruvate. It consists of several steps, each catalyzed by a specific enzyme. One of the key steps in glycolysis is the conversion of 3-phosphoglyceraldehyde (PGAL) to 1,3-bisphosphoglycerate (BPG).
Here is a detailed explanation of this step:
1. Conversion of glucose to glucose-6-phosphate:
This is the first step of glycolysis and is catalyzed by the enzyme hexokinase. Glucose is phosphorylated using ATP to form glucose-6-phosphate. This step traps glucose inside the cell and prepares it for further metabolism.
2. Conversion of glucose-6-phosphate to fructose-6-phosphate:
In the second step, the enzyme glucose-6-phosphate isomerase converts glucose-6-phosphate into its isomer, fructose-6-phosphate.
3. Conversion of fructose-6-phosphate to fructose 1,6-bisphosphate:
This step is catalyzed by the enzyme phosphofructokinase-1 (PFK-1). Fructose-6-phosphate is phosphorylated using ATP to form fructose 1,6-bisphosphate. This is an important regulatory step in glycolysis and is irreversible.
4. Cleavage of fructose 1,6-bisphosphate:
The enzyme aldolase catalyzes the cleavage of fructose 1,6-bisphosphate into two three-carbon molecules: dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (G3P). DHAP isomerizes to form another G3P molecule.
5. Conversion of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG):
This is the step where NADH + H+ is formed. The enzyme glyceraldehyde 3-phosphate dehydrogenase catalyzes the oxidation of G3P. In this process, NAD+ is reduced to NADH + H+. The energy released in this oxidation is used to phosphorylate G3P, forming 1,3-bisphosphoglycerate (BPG).
Overall, this step is crucial for the generation of high-energy molecules like NADH, which are essential for ATP production in subsequent steps of glycolysis and cellular respiration. The NADH produced in this step will go on to donate its high-energy electrons to the electron transport chain, leading to the production of more ATP.
Glycolysis is the metabolic pathway that converts glucose into pyruvate. It consists of several steps, each catalyzed by a specific enzyme. One of the key steps in glycolysis is the conversion of 3-phosphoglyceraldehyde (PGAL) to 1,3-bisphosphoglycerate (BPG).
Here is a detailed explanation of this step:
1. Conversion of glucose to glucose-6-phosphate:
This is the first step of glycolysis and is catalyzed by the enzyme hexokinase. Glucose is phosphorylated using ATP to form glucose-6-phosphate. This step traps glucose inside the cell and prepares it for further metabolism.
2. Conversion of glucose-6-phosphate to fructose-6-phosphate:
In the second step, the enzyme glucose-6-phosphate isomerase converts glucose-6-phosphate into its isomer, fructose-6-phosphate.
3. Conversion of fructose-6-phosphate to fructose 1,6-bisphosphate:
This step is catalyzed by the enzyme phosphofructokinase-1 (PFK-1). Fructose-6-phosphate is phosphorylated using ATP to form fructose 1,6-bisphosphate. This is an important regulatory step in glycolysis and is irreversible.
4. Cleavage of fructose 1,6-bisphosphate:
The enzyme aldolase catalyzes the cleavage of fructose 1,6-bisphosphate into two three-carbon molecules: dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (G3P). DHAP isomerizes to form another G3P molecule.
5. Conversion of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG):
This is the step where NADH + H+ is formed. The enzyme glyceraldehyde 3-phosphate dehydrogenase catalyzes the oxidation of G3P. In this process, NAD+ is reduced to NADH + H+. The energy released in this oxidation is used to phosphorylate G3P, forming 1,3-bisphosphoglycerate (BPG).
Overall, this step is crucial for the generation of high-energy molecules like NADH, which are essential for ATP production in subsequent steps of glycolysis and cellular respiration. The NADH produced in this step will go on to donate its high-energy electrons to the electron transport chain, leading to the production of more ATP.
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Which step of glycolysis involves the formation of NADH + H+?a)Convers...
The step of glycolysis that involves the formation of NADH + H+ is the conversion of 3-phosphoglyceraldehyde to 1, 3-bisphosphoglycerate. During this step, the enzyme glyceraldehyde-3-phosphate dehydrogenase catalyzes the oxidation of glyceraldehyde-3-phosphate (3-phosphoglyceraldehyde) and the transfer of electrons to the coenzyme NAD+ (nicotinamide adenine dinucleotide), resulting in the formation of NADH + H+.
Option c) "Conversion of 3-phosphoglyceraldehyde to 1, 3-bisphosphoglycerate" is the correct answer because it correctly identifies the step in glycolysis where NADH + H+ is formed by the oxidation of 3-phosphoglyceraldehyde.
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Which step of glycolysis involves the formation of NADH + H+?a)Conversion of glucose to glucose-6-phosphateb)Conversion of fructose-6-phosphate to fructose 1, 6-bisphosphatec)Conversion of 3-phosphoglyceraldehyde to 1, 3-bisphosphoglycerated)Conversion of phosphoenolpyruvate (PEP) to pyruvic acidCorrect answer is option 'C'. Can you explain this answer?
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