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All enzymes of the TCA cycle are located in the mitochondrial matrix, except one which is located in inner mitochondrial membranes in eukaryotes. This enzyme is
- a)isocitrate dehydrogenase
- b)malate dehydrogenase
- c)lactate dehydrogenase
- d)succinate dehydrogenase
Correct answer is option 'D'. Can you explain this answer?
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All enzymes of the TCA cycle are located in the mitochondrial matrix, ...
Overview of the TCA Cycle
The Tricarboxylic Acid (TCA) cycle, also known as the Krebs cycle, is a crucial metabolic pathway that occurs in the mitochondrial matrix of eukaryotic cells. It plays a key role in energy production through the oxidation of acetyl-CoA.
Enzymes of the TCA Cycle
Most of the enzymes involved in the TCA cycle reside in the mitochondrial matrix, facilitating various reactions that convert substrates into energy-rich molecules.
Succinate Dehydrogenase: The Exception
- **Location**: Unlike other TCA cycle enzymes, succinate dehydrogenase is located in the inner mitochondrial membrane.
- **Function**: It catalyzes the oxidation of succinate to fumarate, while simultaneously reducing FAD to FADH2, which is an important electron carrier in the electron transport chain.
Importance of Inner Membrane Location
- **Integration with Electron Transport**: The positioning of succinate dehydrogenase in the inner mitochondrial membrane allows it to directly participate in both the TCA cycle and the electron transport chain. This dual role enhances the efficiency of ATP production.
- **Energy Yield**: The FADH2 generated by succinate dehydrogenase enters the electron transport chain, contributing to the proton gradient essential for ATP synthesis.
Conclusion
In summary, succinate dehydrogenase is unique among TCA cycle enzymes due to its location in the inner mitochondrial membrane, allowing it to bridge the TCA cycle and oxidative phosphorylation effectively. This positioning is vital for maximizing energy production in eukaryotic cells.
The Tricarboxylic Acid (TCA) cycle, also known as the Krebs cycle, is a crucial metabolic pathway that occurs in the mitochondrial matrix of eukaryotic cells. It plays a key role in energy production through the oxidation of acetyl-CoA.
Enzymes of the TCA Cycle
Most of the enzymes involved in the TCA cycle reside in the mitochondrial matrix, facilitating various reactions that convert substrates into energy-rich molecules.
Succinate Dehydrogenase: The Exception
- **Location**: Unlike other TCA cycle enzymes, succinate dehydrogenase is located in the inner mitochondrial membrane.
- **Function**: It catalyzes the oxidation of succinate to fumarate, while simultaneously reducing FAD to FADH2, which is an important electron carrier in the electron transport chain.
Importance of Inner Membrane Location
- **Integration with Electron Transport**: The positioning of succinate dehydrogenase in the inner mitochondrial membrane allows it to directly participate in both the TCA cycle and the electron transport chain. This dual role enhances the efficiency of ATP production.
- **Energy Yield**: The FADH2 generated by succinate dehydrogenase enters the electron transport chain, contributing to the proton gradient essential for ATP synthesis.
Conclusion
In summary, succinate dehydrogenase is unique among TCA cycle enzymes due to its location in the inner mitochondrial membrane, allowing it to bridge the TCA cycle and oxidative phosphorylation effectively. This positioning is vital for maximizing energy production in eukaryotic cells.
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All enzymes of the TCA cycle are located in the mitochondrial matrix, ...
All enzymes of the TCA cycle are present in the mitochondrial matrix, except succinate dehydrogenase.
Succinate dehydrogenase is tightly bound to the inner mitochondrial membrane in eukaryotes and to the plasma membrane in prokaryotes.
Succinate dehydrogenase is tightly bound to the inner mitochondrial membrane in eukaryotes and to the plasma membrane in prokaryotes.
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All enzymes of the TCA cycle are located in the mitochondrial matrix, except one which is located in inner mitochondrial membranes in eukaryotes. This enzyme isa)isocitrate dehydrogenaseb)malate dehydrogenasec)lactate dehydrogenased)succinate dehydrogenaseCorrect answer is option 'D'. Can you explain this answer?
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All enzymes of the TCA cycle are located in the mitochondrial matrix, except one which is located in inner mitochondrial membranes in eukaryotes. This enzyme isa)isocitrate dehydrogenaseb)malate dehydrogenasec)lactate dehydrogenased)succinate dehydrogenaseCorrect answer is option 'D'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about All enzymes of the TCA cycle are located in the mitochondrial matrix, except one which is located in inner mitochondrial membranes in eukaryotes. This enzyme isa)isocitrate dehydrogenaseb)malate dehydrogenasec)lactate dehydrogenased)succinate dehydrogenaseCorrect answer is option 'D'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for All enzymes of the TCA cycle are located in the mitochondrial matrix, except one which is located in inner mitochondrial membranes in eukaryotes. This enzyme isa)isocitrate dehydrogenaseb)malate dehydrogenasec)lactate dehydrogenased)succinate dehydrogenaseCorrect answer is option 'D'. Can you explain this answer?.
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