Which of the following sentences about immunoglobulin is true?a)IgG is...
IgA is the most abundant immunoglobulin in body fluids and the second most abundant immunoglobulin in plasma. IgG is the most abundant and diverse antibody in plasma.
Which of the following sentences about immunoglobulin is true?a)IgG is...
Explanation:
Background:
Immunoglobulins, also known as antibodies, are proteins produced by the immune system in response to foreign substances (antigens) such as bacteria, viruses, or allergens. There are five main classes of immunoglobulins: IgG, IgM, IgA, IgD, and IgE. Each class has specific functions and characteristics.
Correct Answer: B - IgG is the most abundant immunoglobulin in body fluids.
Explanation:
IgG is the most abundant immunoglobulin class in the body fluids, including blood, lymph, and cerebrospinal fluid. It constitutes approximately 75-80% of the total immunoglobulin pool in the body.
Incorrect Answer A: IgG is the first immunoglobulin to respond to an infection.
This statement is incorrect. IgM is the first immunoglobulin to respond to an infection. It is produced early in the immune response and plays a crucial role in the primary immune response.
Incorrect Answer C: IgD functions as an antigen receptor of the B cell.
This statement is incorrect. IgD is primarily found on the surface of mature B cells, where it acts as a membrane-bound antigen receptor. Its exact function is not fully understood, but it is believed to play a role in the activation and regulation of B cells.
Incorrect Answer D: IgE level increases during allergy attacks.
This statement is incorrect. IgE is involved in allergic responses and is responsible for triggering the release of histamine and other inflammatory mediators during an allergic reaction. However, IgE levels do not necessarily increase during allergy attacks. IgE levels may already be elevated in individuals with allergies, and exposure to allergens can lead to the activation of IgE-bound mast cells and basophils, causing the release of inflammatory mediators.
Conclusion:
Among the given options, the correct statement about immunoglobulin is that IgG is the most abundant immunoglobulin in body fluids. It comprises a significant portion of the total immunoglobulin pool and plays a crucial role in immune defense against pathogens.
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