Software Development Exam > Software Development Questions > Internal ribosome entry site IRES presence in...
Start Learning for Free
Internal ribosome entry site IRES presence in mRNA aids with:
- a)inhibits its translation
- b)promotes post transcription processing
- c)promotes its translation under adverse conditions
- d)has no impact on its translation
Correct answer is option 'C'. Can you explain this answer?
Verified Answer
Internal ribosome entry site IRES presence in mRNA aids with:a)inhibit...
Concept:
- Internal ribosome entry sites (IRESs) are sequences within the RNA molecule that allow binding of ribosomes without scanning.
- Theyplay an important part in allowing certain animal viruses, notably the picornaviruses, to evade the constraints of ribosomal scanning.
Explanation:
Fig 1: IRES mediated translation
- Internal ribosomal entry sites (IRESs) are regions in the mRNAs that allow the internal initiation of translation.
- Indeed, even though the vast majority of cellular mRNAs are translated by the cap-dependent mechanisms.
- It is now known that, in certain cases, translation can also occur in a cap-independent manner, thanks to specific mRNA sequences able to recruit the 40S ribosomal subunit in the vicinity of an AUG starting codon.
- The first IRES was identified in the genome of poliovirus (PV) and encephalomyocarditis virus (EMCV), and later in many other viruses.
- During infection, the cap-dependent translation of the cell is impaired, and the viral RNAs use the internal initiation for their gene expression.
hence the correct answer is option 3
Most Upvoted Answer
Internal ribosome entry site IRES presence in mRNA aids with:a)inhibit...
Internal Ribosome Entry Site (IRES) Presence in mRNA
Internal Ribosome Entry Site (IRES) is a specific region within the mRNA molecule that allows for cap-independent translation initiation. This means that translation can occur even under adverse conditions where the traditional cap-dependent translation may be inhibited.
Role of IRES in mRNA Translation
- Promotes Translation Under Adverse Conditions: One of the key functions of IRES in mRNA is to promote translation under adverse conditions such as cellular stress or viral infections. In these situations, the cap-dependent translation may be compromised, but IRES can bypass the need for a 5' cap structure and initiate translation efficiently.
- Enhances Protein Synthesis Efficiency: IRES elements can enhance the efficiency of protein synthesis by allowing for the recruitment of ribosomes directly to the mRNA molecule without the need for cap recognition. This can be particularly important in situations where protein synthesis needs to be maintained under stress conditions.
- Regulates Gene Expression: The presence of IRES elements in mRNA can also play a role in regulating gene expression by influencing the translation of specific transcripts. This can have implications for various cellular processes and responses to environmental stimuli.
- Facilitates Viral Protein Synthesis: Viruses often utilize IRES elements in their mRNA to ensure the efficient translation of viral proteins within host cells. This allows viruses to hijack the host cell machinery for their own replication and survival.
In conclusion, the presence of IRES in mRNA plays a crucial role in promoting translation under adverse conditions, enhancing protein synthesis efficiency, regulating gene expression, and facilitating viral protein synthesis. It is a significant mechanism that allows for the adaptation of cells to stressful environments and can have implications for various biological processes.
Internal Ribosome Entry Site (IRES) is a specific region within the mRNA molecule that allows for cap-independent translation initiation. This means that translation can occur even under adverse conditions where the traditional cap-dependent translation may be inhibited.
Role of IRES in mRNA Translation
- Promotes Translation Under Adverse Conditions: One of the key functions of IRES in mRNA is to promote translation under adverse conditions such as cellular stress or viral infections. In these situations, the cap-dependent translation may be compromised, but IRES can bypass the need for a 5' cap structure and initiate translation efficiently.
- Enhances Protein Synthesis Efficiency: IRES elements can enhance the efficiency of protein synthesis by allowing for the recruitment of ribosomes directly to the mRNA molecule without the need for cap recognition. This can be particularly important in situations where protein synthesis needs to be maintained under stress conditions.
- Regulates Gene Expression: The presence of IRES elements in mRNA can also play a role in regulating gene expression by influencing the translation of specific transcripts. This can have implications for various cellular processes and responses to environmental stimuli.
- Facilitates Viral Protein Synthesis: Viruses often utilize IRES elements in their mRNA to ensure the efficient translation of viral proteins within host cells. This allows viruses to hijack the host cell machinery for their own replication and survival.
In conclusion, the presence of IRES in mRNA plays a crucial role in promoting translation under adverse conditions, enhancing protein synthesis efficiency, regulating gene expression, and facilitating viral protein synthesis. It is a significant mechanism that allows for the adaptation of cells to stressful environments and can have implications for various biological processes.
|
Explore Courses for Software Development exam
|
|
Similar Software Development Doubts
Top Courses for Software DevelopmentView all
Internal ribosome entry site IRES presence in mRNA aids with:a)inhibits its translation b)promotes post transcription processing c)promotes its translation under adverse conditionsd)has no impact on its translationCorrect answer is option 'C'. Can you explain this answer?
Question Description
Internal ribosome entry site IRES presence in mRNA aids with:a)inhibits its translation b)promotes post transcription processing c)promotes its translation under adverse conditionsd)has no impact on its translationCorrect answer is option 'C'. Can you explain this answer? for Software Development 2025 is part of Software Development preparation. The Question and answers have been prepared according to the Software Development exam syllabus. Information about Internal ribosome entry site IRES presence in mRNA aids with:a)inhibits its translation b)promotes post transcription processing c)promotes its translation under adverse conditionsd)has no impact on its translationCorrect answer is option 'C'. Can you explain this answer? covers all topics & solutions for Software Development 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Internal ribosome entry site IRES presence in mRNA aids with:a)inhibits its translation b)promotes post transcription processing c)promotes its translation under adverse conditionsd)has no impact on its translationCorrect answer is option 'C'. Can you explain this answer?.
Internal ribosome entry site IRES presence in mRNA aids with:a)inhibits its translation b)promotes post transcription processing c)promotes its translation under adverse conditionsd)has no impact on its translationCorrect answer is option 'C'. Can you explain this answer? for Software Development 2025 is part of Software Development preparation. The Question and answers have been prepared according to the Software Development exam syllabus. Information about Internal ribosome entry site IRES presence in mRNA aids with:a)inhibits its translation b)promotes post transcription processing c)promotes its translation under adverse conditionsd)has no impact on its translationCorrect answer is option 'C'. Can you explain this answer? covers all topics & solutions for Software Development 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Internal ribosome entry site IRES presence in mRNA aids with:a)inhibits its translation b)promotes post transcription processing c)promotes its translation under adverse conditionsd)has no impact on its translationCorrect answer is option 'C'. Can you explain this answer?.
Solutions for Internal ribosome entry site IRES presence in mRNA aids with:a)inhibits its translation b)promotes post transcription processing c)promotes its translation under adverse conditionsd)has no impact on its translationCorrect answer is option 'C'. Can you explain this answer? in English & in Hindi are available as part of our courses for Software Development.
Download more important topics, notes, lectures and mock test series for Software Development Exam by signing up for free.
Here you can find the meaning of Internal ribosome entry site IRES presence in mRNA aids with:a)inhibits its translation b)promotes post transcription processing c)promotes its translation under adverse conditionsd)has no impact on its translationCorrect answer is option 'C'. Can you explain this answer? defined & explained in the simplest way possible. Besides giving the explanation of
Internal ribosome entry site IRES presence in mRNA aids with:a)inhibits its translation b)promotes post transcription processing c)promotes its translation under adverse conditionsd)has no impact on its translationCorrect answer is option 'C'. Can you explain this answer?, a detailed solution for Internal ribosome entry site IRES presence in mRNA aids with:a)inhibits its translation b)promotes post transcription processing c)promotes its translation under adverse conditionsd)has no impact on its translationCorrect answer is option 'C'. Can you explain this answer? has been provided alongside types of Internal ribosome entry site IRES presence in mRNA aids with:a)inhibits its translation b)promotes post transcription processing c)promotes its translation under adverse conditionsd)has no impact on its translationCorrect answer is option 'C'. Can you explain this answer? theory, EduRev gives you an
ample number of questions to practice Internal ribosome entry site IRES presence in mRNA aids with:a)inhibits its translation b)promotes post transcription processing c)promotes its translation under adverse conditionsd)has no impact on its translationCorrect answer is option 'C'. Can you explain this answer? tests, examples and also practice Software Development tests.
|
|
Explore Courses for Software Development exam
|
|
Signup for Free!
Signup to see your scores go up within 7 days! Learn & Practice with 1000+ FREE Notes, Videos & Tests.
|
© EduRev
|
Education Revolution
|
|
Signup to see your scores
go up within 7 days!
Access 1000+ FREE Docs, Videos and Tests
Takes less than 10 seconds to signup