Assertion : Prothrombinase enzyme act as antiheparin.Reason : Heparin ...
Prothrombinase enzyme is necessary for blood clotting. It acts as antiheparin. Coagulation of blood in vessels is prevented by heparin, a quick acting anticoagulant. It inhibits conversion of prothrombin to thrombin and is used in open-heart surgery.
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Assertion : Prothrombinase enzyme act as antiheparin.Reason : Heparin ...
Understanding the Assertion and Reason
The assertion states that "Prothrombinase enzyme acts as antiheparin," while the reason explains that "Heparin prevents coagulation of blood in blood vessels."
Analysis of the Assertion
- Prothrombinase is an enzyme complex essential for the conversion of prothrombin to thrombin, which is crucial in the coagulation cascade.
- While it plays a significant role in promoting blood clotting, it does not act as an antiheparin.
Analysis of the Reason
- Heparin is an anticoagulant that inhibits blood clotting by enhancing the activity of antithrombin III, which in turn inhibits thrombin and factor Xa.
- Heparin indeed prevents coagulation, but it does not relate directly to the role of prothrombinase.
Conclusion
- Both the assertion and reason are true statements:
- Prothrombinase is involved in blood coagulation.
- Heparin prevents blood coagulation.
- However, the reason does not provide a correct explanation for the assertion since prothrombinase does not function as an antiheparin.
Final Evaluation
Thus, the correct answer is option 'B': Both Assertion and Reason are true, but Reason is not the correct explanation of Assertion. This distinction helps clarify the roles of these components in the coagulation process and their respective functions in hemostasis.