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“Cycloporin-A” bioactive agent that is commonly used as immunosuppressive drug is the product by the fungus that is
  • a)
    Monascus purpureus
  • b)
    Trichoderm polysponum
  • c)
    Aspergillus niger
  • d)
    Propioni bacterium sharmanii
Correct answer is option 'B'. Can you explain this answer?
Verified Answer
“Cycloporin-A” bioactive agent that is commonly used as immunosuppress...
Cyclosporine A is widely produced by submerged fermentation of aerobic fungi identified as Trichoderma polysporum but currently identified as Tolypocladium inflatum. 
Since its discovery, very few studies have been carried out to search for other microbial sources for its production. Most of the research work on cyclosporine A is based on fungi Tolypocladium inflatum and Aspergillus terreus.
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Most Upvoted Answer
“Cycloporin-A” bioactive agent that is commonly used as immunosuppress...

The bioactive agent Cyclosporin-A, which is commonly used as an immunosuppressive drug, is produced by the fungus Trichoderma polysporum. Here is a detailed explanation:
1. Cyclosporin-A:
- Cyclosporin-A is a potent immunosuppressive drug that is widely used in organ transplantation to prevent rejection.
- It is also used to treat autoimmune diseases such as rheumatoid arthritis and psoriasis.
2. Production by Fungus:
- Cyclosporin-A is produced by a specific strain of the fungus Trichoderma polysporum.
- This fungus is known for its ability to produce secondary metabolites with pharmaceutical importance.
3. Other Options:
- Monascus purpureus is a fungus used in the production of red yeast rice, which is used as a dietary supplement.
- Aspergillus niger is a common fungus used in the production of various enzymes and organic acids.
- Propionibacterium shermanii is a bacterium used in the production of propionic acid and Swiss cheese.
4. Conclusion:
- Among the given options, Trichoderma polysporum is the fungus that produces Cyclosporin-A.
- Its immunosuppressive properties make it valuable in the field of medicine for preventing organ rejection and treating autoimmune diseases.
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Community Answer
“Cycloporin-A” bioactive agent that is commonly used as immunosuppress...
Yes option B is correct refer NCERT ..chap 10...page 183
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“Cycloporin-A” bioactive agent that is commonly used as immunosuppressive drug is the product by the fungus that isa)Monascus purpureusb)Trichoderm polysponumc)Aspergillus nigerd)Propioni bacterium sharmaniiCorrect answer is option 'B'. Can you explain this answer?
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